重楼复方抗肿瘤研究进展  

Research Progress and Anti-tumor of Paridis Rhizoma Compound

作　　者：王萌萌 徐旭[2,3] 王丽[1] 杨玥 林娟[4] 徐科一 李楚源[4] 李鹏 WANG Mengmeng;XU Xu;WANG Li;YANG Yue;LIN Juan;XU Keyi;LI Chuyuan;LI Peng(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine,Tianjin Institute of Pharmaceutical Research,Tianjin 300301,China;National Key Laboratory of Drug Formation Evaluation and Systematic Transformation,Tianjin 300301,China;Hutchison Whampoa Guangzhou Bai Yunshan Chinese Medicine Co.,Ltd.,Guangdong Province,Guangzhou 510515,China)

机构地区：[1]天津中医药大学,天津301617 [2]天津药物研究院天津市中药质量标志物重点实验室,天津300301 [3]天津药物研究院药物成药性评价与系统转化全国重点实验室,天津300301 [4]广州白云山和记黄埔中药有限公司,广东广州510515

出　　处：《光明中医》2024年第18期3678-3681,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：中医常以扶正解毒法治疗癌症。清热解毒类中药重楼常与其他中药配伍进行抗肿瘤治疗。研究表明重楼复方可抑制肿瘤生长、侵袭及转移、逆转多药耐药、提高免疫水平、调节肠道菌群及癌细胞代谢发挥抗肿瘤作用。重楼复方在临床上已被应用于多种癌症的治疗。重楼复方可单独应用改善患者症状,也可通过联合化疗、放疗、常规治疗等提高治疗效果。Traditional Chinese medicine often treats cancer by strengthening the body resistance and detoxification.Heat-clearing and detoxifying Chinese medicine Paridis Rhizoma is often combined with other Chinese medicine for anti-tumor treatment.Studies have shown that Paridis Rhizoma compound can inhibit tumor growth,invasion and metastasis,reverse multi-drug resistance,improve immune level,regulate intestinal flora and cancer cell metabolism to play an anti-tumor role.Paridis Rhizoma compound has been used in the treatment of many kinds of cancer.Paridis Rhizoma compound can be used alone to improve the symptoms of patients,and can also improve the therapeutic effect through combination chemotherapy,radiotherapy,conventional treatment,etc.

关 键 词：重楼 抗肿瘤 药理作用 综述 

分 类 号：R273[医药卫生—中西医结合]