新乡地区1282例女性泌尿生殖道支原体感染特征分析  

Epidemiological analysis of 1282 cases of female urogenital Mycoplasma infection in Xinxiang area

作　　者：曹献芹 马建敏[2] 张晓菲 陈冉 CAO Xianqin;MA Jianmin;ZHANG Xiaofei;CHEN Ran(Xinxiang Central Hospital/The fourth Clinical College of Xinxiang Medical University,Xinxiang 453000,Henan,China;Laboratory Department,Xinxiang Center for Disease Control and Prevention)

机构地区：[1]新乡市中心医院/新乡医学院第四临床学院检验科,河南新乡453000 [2]新乡市疾病预防控制中心检验科

出　　处：《中国病原生物学杂志》2024年第11期1322-1326,共5页Journal of Pathogen Biology

摘　　要：目的通过分析疑似为泌尿生殖道感染患者的泌尿生殖道标本,探析新乡地区女性泌尿生殖道支原体感染流行病学特点,以期为临床治疗提供参考意见。方法选取2021-2023年本院检验科收到的1282份来自妇产科、泌尿科送检的疑似为泌尿生殖道感染女性患者的泌尿生殖道标本。采用支原体培养鉴定药敏试剂盒进行解脲脲原体(ureaplasma urealyticum,Uu)和人型支原体(mycoplasma hominis,Mh)培养检测及药敏试验。对比分析不同年份、不同临床症状特点、不同年龄组患者支原体阳性率及不同年份检出的支原体对常用抗生素的耐药率。结果2021-2023年共送检标本1282份,支原体阳性率44.46%(570/1282),456份为单纯Uu阳性(35.57%,456/1282),14份为单纯Mh阳性(1.09%,14/1282),100份为Uu和Mh混合感染阳性(7.80%,100/1282)。2021-2023年,泌尿生殖道支原体总阳性率呈逐年下降趋势,Uu阳性率下降、Uu和Mh混合阳性率上升,差异有统计学意义(P<0.05)。合并临床症状组患者共送检标本442份,支原体阳性率49.55%(219/442),176份为单纯Uu阳性(39.82%,176/442),5份为单纯Mh阳性(1.13%,5/442),38份为Uu和Mh混合感染(8.60%,38/442)。无症状组患者共送检标本840份,支原体阳性率41.79%(351/840),280份为单纯Uu阳性(33.33%,280/840),9份为单纯Mh阳性(1.07%,9/840),62份为Uu和Mh混合感染(7.38%,62/840)。合并临床症状组患者支原体总阳性率、Uu阳性率、Uu和Mh混合感染阳性率均高于无症状组患者,其中支原体总阳性率、Uu阳性率差异有统计学意义(P<0.05)。<20岁患者支原体阳性率58.33%(7/12),20~29岁患者支原体阳性率50.29%(259/515),30~39岁患者支原体阳性率41.73%(212/508),40~49岁患者支原体阳性率40.23%(70/174),≥50岁患者支原体阳性率30.14%(22/73),不同年龄泌尿生殖道支原体阳性率差异有统计学意义(P<0.05)。单纯Uu阳性率在30~39岁患者中最高,单纯Mh及Uu和Mh混合感染阳性率在<20岁患者中最高Objective By analyzing the urogenital specimens of patients suspected of having urogenital tract infections,this study explored the epidemiological characteristics of urogenital mycoplasma infections in women in Xinxiang area,with the expectation of providing reference opinions for clinical treatment.Methods From 2021 to 2023,1282 urogenital tract specimens from female patients suspected of having urogenital tract infections and sent for examination by the departments of obstetrics and gynecology and urology to the clinical laboratory of our hospital were selected.The culture and identification drug sensitivity kits for Ureaplasma urealyticum(Uu)and Mycoplasma hominis(Mh)were used for Mycoplasma culture detection and drug sensitivity tests.A comparative analysis was conducted on the positive rates of Mycoplasma in patients of different years,with different clinical symptom characteristics and in different age groups,as well as the resistance rates of Mycoplasma detected in different years to commonly used antibiotics.Results From 2021 to 2023,a total of 1282 specimens were submitted for examination.The positive rate of Mycoplasma was 44.46%(570/1282),456 were positive for Uu alone(35.57%,456/1282),14 were positive for Mh alone(1.09%,14/1282),and 100 were positive for mixed infection of Uu and Mh(7.80%,100/1282).From 2021 to 2023,the total positive rate of urogenital tract Mycoplasma showed a decreasing trend year by year.The positive rate of Uu decreased,and the positive rate of the mixed infection of Uu and Mh increased.The difference was statistically significant(P<0.05).A total of 442 specimens were submitted for examination from the patients in the combined clinical symptom group.The positive rate of Mycoplasma was 49.55%(219/442),176 specimens were positive for Uu alone(39.82%,176/442),5 specimens were positive for Mh alone(1.13%,5/442),and 38 specimens were co-infected with Uu and Mh(8.60%,38/442).A total of 840 specimens were submitted for examination from the patients in the asymptomatic group.The positiv

关 键 词：泌尿生殖道 支原体 耐药性 

分 类 号：R711.3[医药卫生—妇产科学]