血友病性假肿瘤的临床与影像学分析  

Analysis of the clinical and imaging characteristics of hemophilic pseudotumor

作　　者：刘春蕾 王宇飞 李英 LIU Chunlei;WANG Yufei;LI Ying(State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Haihe Laboratory of Cell Ecosystem,Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China;Department of Radiotherapy,Tianjin Medical University Cancer Institute and Hospital,Tianjin 300060,China)

机构地区：[1]中国医学科学院血液病医院(中国医学科学院血液学研究所)实验血液学国家重点实验室国家血液系统疾病临床医学研究中心,细胞生态海河实验室天津医学健康研究院,天津300020 [2]天津医科大学肿瘤医院放疗科,天津300060

出　　处：《医学影像学杂志》2024年第9期106-109,共4页Journal of Medical Imaging

摘　　要：目的探讨血友病性假肿瘤(HP)患者的临床和影像学特征。方法选取24例经临床、影像学及实验室检查确诊的血友病性假肿瘤患者的临床及影像学资料。结果24例患者中甲型22例,乙型2例;轻型4例,中型2例,重型18例。重型、轻型及中型患者之间外伤发生率差异无统计学意义(P>0.05)。血友病性假肿瘤高发年龄为20~39岁,占总血友病性假肿瘤人数的45.8%。24例患者共发现38个病灶,其中软组织型23个病灶,骨骼内型12个病灶,骨膜下型3个病灶;主要影像学表现为软组织肿块,单发或多发囊样或膨胀性骨质破坏、破坏边缘骨质硬化、骨膜反应及骨皮质受压吸收。部分病变存在点状及不规则形钙化。结论血友病性假肿瘤好发于青壮年血友病患者,其具有特定的影像学特征,结合病史可以明确诊断。Objective To illustrate the variable radiologic appearance of hemophilic pseudotumors in musculoskeletal systems as shown by radiography,CT and MRI.Methods The clinical feature and the imaging findings of 24 patients with hemophilia were analyzed in this retrospective study.Results In 24 cases of hemophilic pseudotumors,there were 22 cases of hemophilia A and 2 cases of hemophilia B.There was no statistical significance in the incidence of trauma among severe patients,mild patients and moderate patients(P>0.05).There were 23 soft-Tissue lesions,3 subperiosteal lesions,and 12 intraosseous lesions of all the 24 patients.Main image findings included soft tissue swelling or lump,bone destruction with edge sclerosis,osteolysis lesion.Conclusions Hemophilic pseudotumor has radiographically variable appearances.Hemophilic history of patients can contribute to the right diagnosis of pseudotumor.

关 键 词：血友病 假肿瘤 体层摄影术 X线计算机 磁共振成像 

分 类 号：R445[医药卫生—影像医学与核医学] R554[医药卫生—诊断学]