瑞巴派特联合铝镁加混悬液对应激性胃溃疡患者症状改善及睡眠质量效果研究  

Study on Symptoms and Sleep Effect of Rebabapide Combined with Aluminum Magnesium and Suspension in Patients with Stress Gastric Ulcer

作　　者：温启元 WEN Qiyuan(Department of Gastroenterology,Changle District Second Hospital,Fuzhou 350200,China)

机构地区：[1]福州市长乐区第二医院消化内科,福州350200

出　　处：《世界睡眠医学杂志》2024年第7期1444-1446,共3页World Journal of Sleep Medicine

摘　　要：目的:分析应激性胃溃疡治疗中采取瑞巴派特联合铝镁加混悬液的治疗效果及对症状改善与睡眠质量的影响。方法:选取2022年1月至2023年9月福州市长乐区第二医院收治的应激性胃溃疡患者50例作为研究对象,按照随机数字表法分为对照组和观察组,每组25例。对照组采取常规治疗,观察组采取瑞巴派特联合铝镁加混悬液治疗,比较2组治疗后症状改善时间(上腹痛、反酸、腹胀、烧心),分析2组治疗前后睡眠情况、睡眠相关评分。结果:观察组治疗后临床症状改善时间较对照组更短,差异有统计学意义(P<0.05);治疗后比较观察组与对照组睡眠时长、闭眼至入睡时间、匹兹堡睡眠质量指数、阿森斯失眠量表评分可见前者较后者改善明显,差异有统计学意义(P<0.05)。结论:对应激性胃溃疡患者采取瑞巴派特联合铝镁加混悬液治疗可改善其临床症状,与常规治疗模式比较还能缓解其睡眠状态,延长睡眠时间,有助于身体康复,值得推广。Objective:To analyze the therapeutic effect of using remifentanil combined with aluminum magnesium suspension in the treatment of stress gastric ulcers,and its impact on symptom improvement and sleep quality.Methods:Fifty patients with stress-induced gastric ulcers admitted to the Second Hospital of Changle District,Fuzhou City From January 2022 to September 2023 were selected as the study subjects.They were randomly divided into two groups:the control group(25 cases)received routine treatment,and the observation group(25 cases)received treatment with remifentanil combined with aluminum magnesium suspension.The time for symptom improvement(upper abdominal pain,acid reflux,abdominal distension,and heartburn)after treatment was compared between the two groups.The sleep status and sleep related scores before and after treatment were analyzed between the two groups.Results:After treatment,the improvement time of clinical symptoms in observation group was shorter than that in control group(P<0.05).After treatment,the sleep duration,time from closing eyes to falling asleep,Pittsburgh sleep quality index and Athens insomnia Scale score of the observation group were significantly improved compared with the control group,and the difference was statistically significant(P<0.05).Conclusion:The combination of remifentanil and aluminum magnesium suspension can improve the clinical symptoms of patients with stress gastric ulcers.Compared with conventional treatment modes,it can also alleviate their sleep status,prolong sleep time,and contribute to physical recovery,which is worth promoting.

关 键 词：胃溃疡 瑞巴派特 铝镁加混悬液 应激性溃疡 胃黏膜疾病 睡眠质量 反酸 烧心 

分 类 号：R338.63[医药卫生—人体生理学] R573.1[医药卫生—基础医学]