多项A族链球菌咽炎诊治指南实验室诊断部分的比较与解读  

Comparison and interpretation of laboratory diagnosis of Group A Streptococcus pharyngitis in different guidelines

作　　者：郭孟杨 岳帆 陈思语 候向萍 杨颖 邓江红[4] 姚开虎 Guo Mengyang;Yue Fan;Chen Siyu;Hou Xiangping;Yang Ying;Deng Jianghong;Yao Kaihu(Key Laboratory of Major Diseases in Children,Ministry of Education,National Clinical Research Center for Respiratory Diseases,National Key Discipline of Pediatrics,Laboratory of Infection and Microbiology,Bejing Pediatric Research Institute,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China;Department of Laboratory,Sir Run Run Shaw Alar Hospital,Zhejiang University School of Medicine,Alar 843300,China;Department of Pediatrics,Beijing Shijingshan Hospital,Capital Medical University,Beijing 100043,China;Department of Rheumatology,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China)

机构地区：[1]国家儿童医学中心,首都医科大学附属北京儿童医院,北京市儿科研究所感染与微生物研究室,国家呼吸系统疾病临床医学研究中心,儿科学国家重点学科,儿科重大疾病研究教育部重点实验室,北京100045 [2]浙江大学医学院附属邵逸夫医院新疆兵团阿拉尔医院检验科,阿拉尔843300 [3]首都医科大学石景山教学医院,北京市石景山医院儿科,北京100043 [4]国家儿童医学中心,首都医科大学附属北京儿童医院风湿科,北京100045

出　　处：《中华实用儿科临床杂志》2024年第7期490-494,共5页Chinese Journal of Applied Clinical Pediatrics

基　　金：兵团财政科技计划项目南疆重点产业创新发展支撑计划(2021DB020)。

摘　　要：仅依据临床表现难以准确区分A族链球菌(GAS)与其他病原体所致的咽炎,无法有效指导抗菌药物的合理使用。咽拭子培养、快速抗原检测、核酸检测及血液检测等有助于明确诊断GAS咽炎,但是不同指南对于GAS咽炎实验室检测方法的适用对象、结果解释等建议存在差异。现总结不同GAS咽炎实验室诊断方法及其特点,并对不同指南推荐意见进行分析,为临床诊断和采用抗菌药物治疗GAS咽炎,以及开展相关研究提供参考。It is difficult to accurately distinguish pharyngitis caused by Group A Streptococcus(GAS)from other pathogens according to the clinical presentation alone,which cannot effectively guide the rational use of antimicrobials.The pharyngeal swab culture,rapid antigen detection test,nucleic acid test,and blood test can help definitively diagnose GAS pharyngitis.However,there are differences in different guidelines on who the laboratory test methods are intended for,interpretation of laboratory test results and so on.This article summarizes and analyses the laboratory diagnostic modalities and their characteristics,as well as recommendations for GAS pharyngitis in different guidelines to provide references for the clinical diagnosis,antimicrobial treatment,and further study of GAS pharyngitis.

关 键 词：A族链球菌 化脓性链球菌 咽炎 实验室检测 诊断 

分 类 号：R766.14[医药卫生—耳鼻咽喉科]