西红花主要活性成分的抗炎机制研究进展  

Research Progress on Anti-inflammatory Mechanisms of the Main Active Ingredients in Saffron

作　　者：张淑倩 王玥 吕文豪 王永杰 ZHANG Shuqian;WANG Yue;LYU Wenhao;WANG Yongjie(School of Pharmacy,Hangzhou Normal University,Hangzhou 311121,China)

机构地区：[1]杭州师范大学药学院,浙江杭州311121

出　　处：《杭州师范大学学报（自然科学版）》2024年第5期504-511,共8页Journal of Hangzhou Normal University(Natural Science Edition)

基　　金：杭州师范大学2022年“星光计划”大学生创新创业项目.

摘　　要：西红花的主要成分在多种疾病中发挥抗炎作用.文章综述了西红花中西红花苷和西红花酸2种主要活性成分通过调控Nrf2/HO-1、NF-κB、PI3K/Akt和MAPK等信号通路发挥抗炎作用的研究进展,以期为西红花的临床应用提供理论支撑.Main ingredients of saffron play anti-inflammatory roles in many diseases.This paper reviewed the research progress of the anti-inflammatory effects of two main active ingredients(crocin and crocetin)in saffron through regulating Nrf2/HO-1,NF-κB,PI3K/Akt and MAPK signaling pathways,in order to provide theoretical support for clinical application of saffron.

关 键 词：西红花 西红花苷 西红花酸 炎症 信号通路 

分 类 号：B849[哲学宗教—应用心理学]