Interdisciplinary Research Unveils How SID-1 Recognizes dsRNA and Initiates Systemic RNAi  

作　　者：JIANG Daohua 

机构地区：[1]Institute of Physics,Chinese Academy of Sciences

出　　处：《Bulletin of the Chinese Academy of Sciences》2024年第2期112-113,共2页中国科学院院刊（英文版）

基　　金：supported by the National Natural Science Foundation of China;IOP;CAS

摘　　要：RNA interference(RNAi)is a fascinating biological process in worms,plants,fungi,and metazoans that has been used as a valuable tool in studying gene functions and as therapeutics.In Caenorhabditis elegans,the multipass transmembrane protein,systemic RNA interference defective protein 1(SID-1),has an indispensable role in the uptake and spreading of double-stranded RNA(dsRNA)between cells and tissues,resulting in systemic RNAi.

关 键 词：SID indispensable valuable 

分 类 号：Q78[生物学—分子生物学]