偏振敏感及强度双通道光学相干层析成像方法研究  

Polarization⁃Sensitive and Intensity Dual⁃Channel Optical Coherence Tomographic Method

作　　者：胡燕赵 高万荣[1] Hu Yanzhao;Gao Wanrong(School of Electronic and Optical Engineering,Nanjing University of Science and Technology,Nanjing 210094,Jiangsu,China)

机构地区：[1]南京理工大学电子工程与光电技术学院,江苏南京210094

出　　处：《中国激光》2024年第15期48-57,共10页Chinese Journal of Lasers

基　　金：中央高校基本科研业务费专项资金(30920010003);国家自然科学基金(61275198,60978069)。

摘　　要：报道了一种可实现偏振敏感光学相干层析技术(PSOCT)和光学相干层析技术(OCT)转换的光学相干层析成像系统,其具有单通道分时探测与双通道实时探测功能。搭建了基于单模光纤和偏振控制器的双参考臂探测系统,通过单相机分时或实时采集了水平通道与垂直通道的信号,建立了系统的琼斯矩阵模型,利用斯托克斯参数对得到的断层图像进行处理,获得了相对反射率、延迟和退偏信息,并利用这些信息重建了离体生物组织的强度图、相位延迟图和退偏图。这一过程验证了所提的偏振敏感及强度双通道光学相干层析成像方法的可行性,也展示了已搭建系统的成像能力。所提出的偏振成像系统为PSOCT和谱域OCT的实际临床应用提供了参考。Objective Polarization-sensitive optical coherence tomography(PSOCT)can noninvasively obtain depth-resolved optical tomographic images of biological tissue samples.PSOCT is based on OCT with the additional function of detecting changes in the polarization states of light backscattered from different depths after polarized light is incident on the sample.It can provide polarization-related information about a sample,such as the Stokes parameter,Jones and Mueller matrix,phase delay,and depolarization,and it can distinguish structural specificities that OCT contrast cannot.PSOCT can be applied to detect changes in the function,structure,and activity of human tissues,which has major application prospects in medical diagnosis.In conventional PSOCT,the interference signals from the interferometer output are measured using horizontal and vertical polarization channels,thus requiring two separate spectrometer cameras.This increases the size of the system,adds additional costs,and requires strict triggering of hardware and software to avoid any time delay between the signal acquisition of the two cameras under the phase-based PSOCT algorithm.It also requires high response consistency of the charge-coupled device(CCD).Accordingly,PSOCT technology that utilizes a single spectrometer is currently under development.Some existing PSOCT systems based on a single camera can achieve only time-sharing or real-time detection.In this work,a PS and intensity dual-channel OCT measurement method is presented that can realize both time-sharing and real-time detection,thus providing a new method for laboratories in the analysis of the polarization information of samples.Methods In this study,a theoretical model of a PSOCT system with dual reference arms for a single camera is first established.Based on the traditional spectral-domain OCT(SDOCT)system,an additional reference arm is introduced,where the function of the two reference arms is to provide a pair of orthogonally polarized lights.A neutral filter is added to the other two refere

关 键 词：分时探测 实时探测 双参考臂 单相机 退偏 琼斯矩阵 斯托克斯 强度 相位延迟 

分 类 号：O436[机械工程—光学工程]