Association between heat and upper urinary tract stones morbidity and medical costs: A study in the subtropical humid climate zone  

作　　者：Chen-Lu YANG Jun-Zhe BAO Peng BI Ya-Dong ZHANG Chao-Ming TAN Kai CHEN 

机构地区：[1]College of Public Health,Zhengzhou University,Zhengzhou 450001,China [2]School of Public Health,The University of Adelaide,Adelaide 5000,Australia [3]Department of Andrology,The First Affliated Hospital of Sun Yat-sen University,Guangzhou 510080,China [4]Nanjing Social Insurance Management Center,Nanjing 210008,China [5]Department of Environmental Health Sciences,Yale University,New Haven 06520,USA [6]Yale Center on Climate Change and Health,Yale University,New Haven 06520,USA

出　　处：《Advances in Climate Change Research》2024年第4期717-724,共8页气候变化研究进展（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(42205184);the National Key R&D Program of China(2018YFA0606200);the Guangdong Provincial Health Commission General Project(A2021256).

摘　　要：Urolithiasis is a heat-specific disease.Exploring heat-related urolithiasis susceptibility subtypes,economic burden,and modifying factors could assist governments in targeting interventions to reduce the heat-related health risks of urolithiasis morbidity.We collected data on 23,492 patients with upper urinary tract stones(main subtypes of urolithiasis)from 2013 to 2017 in Nanjing,China.We adopted generalized additive quasi-Poisson models to examine the associations between daily mean temperatures and morbidity of upper urinary tract stones,while generalized additive Gaussian models were used to explore the relationships between temperatures and log-transformed medical costs.We examined the modification effects of disease subtypes(kidney and ureteral calculus),sex,and age through stratified analyses and the modif-cation effects of other meteorological factors by introducing interaction terms in the models.We found that short-term summer heat exposure has a statistically significant effect on ureteral calculus morbidity but not on kidney calculus morbidity.For ureter calculus,a 1℃ temperature increase was associated with a 4.36%(95%confidence interval[CI]:1.94%,6.83%)increase in daily hospitalization and a 5.44%(95%CI:2.71%,8.25%)increase in daily medical costs.The attributable fraction associated with heat(greater than the median value of daily mean temperature,26.8℃)was 7.85%(95%empirical confidence interval[eCI]:3.64%,11.44%)for hospitalization and 9.36%(95%eCI:4.91%,13.14%)for medical costs.The effects of heat on ureter calculus morbidity were significantly higher among the males and those with high sunshine duration than females and those with low sunshine duration.Short-term summer heat exposure was associated with increased morbidity and medical costs of ureteral calculus.Relevant government organizations should take effective intervention measures,including community health education,to reduce the health hazards and economic losses caused by heat.

关 键 词：HEAT Upper urinary tract stones Economic burden Modification effects 

分 类 号：P467[天文地球—大气科学及气象学]