用于检测次氯酸根的二氰基异佛尔酮衍生物的合成及性质研究  

Synthesis and Properties of A Dicyanoisophorone Derivative for the Detection of ClO^(-)

作　　者：汪捷 邓奕 王志宇 胡磊 王慧 WANG Jie;DENG Yi;WANG Zhiyu;HU Lei;WANG Hui(College of Pharmacy,Wannan Medical College,Anhui Wuhu 241002,China)

机构地区：[1]皖南医学院药学院,安徽芜湖241002

出　　处：《广州化工》2024年第19期45-47,共3页GuangZhou Chemical Industry

基　　金：安徽省自然科学基金(1908085QB50);安徽省大学生创新创业教育训练计划项目。

摘　　要：以三苯胺、吩噻嗪和二氰基异佛尔酮为原料,设计合成了一种具有D-D-π-A构型的荧光探针FQ1,借助核磁共振氢谱和质谱对探针的结构进行了表征。利用荧光分光光度计系统地探索了探针FQ1对次氯酸根的识别性能,包括选择性、滴定实验和动力学实验。研究结果表明,探针FQ1对次氯酸根表现出高选择性和高灵敏度,检测限为1.55μM。动力学研究结果表明,加入次氯酸根后,随着时间的增加,探针FQ1的荧光强度逐渐增强,并在120 min后趋于稳定。A D-D-π-A structural fluorescence probe FQ1 was designed and synthesized by using triphenylamine,phenothiazine and dicyanoisophorone as raw materials.The structure of the probe was characterized by 1 H NMR and MS.The identification performance of probe FQ1 response to ClO^(-)was investigated by fluorescence spectrophotometer including selectivity,titration and kinetic experiments.The results demonstrated that probe FQ1 showed high selectivity and sensitivity to ClO^(-)with the detection limit of 1.55μM.Furthermore,the kinetic analysis revealed that the fluorescence intensity of probe FQ1 gradually increased over time upon addition of ClO^(-)until reaching a stable state after 120 min.

关 键 词：次氯酸根 二氰基异佛尔酮 三苯胺 荧光探针 

分 类 号：O657.3[理学—分析化学]