口腔毛滴虫研究进展  

Progress on Trichomonas tenax

作　　者：桂立钦 王永浩 廖晓龙 王继谱 吴星华 高思潮 刘欣超 李文超[1] GUI Li-qin;WANG Yong-hao;LIAO Xiao-long;WANG Ji-pu;WU Xing-hua;GAO Si-chao;LIU Xin-chao;LI Wen-chao(Anhui Province Key Laboratory of Animal Nutritional Regulation and Health,College of Animal Science,Anhui Science and Technology University,Fengyang,Anhui 233100,China)

机构地区：[1]安徽科技学院动物科学学院,动物营养调控与健康安徽省重点实验室,安徽凤阳233100

出　　处：《动物医学进展》2024年第11期111-114,共4页Progress In Veterinary Medicine

基　　金：安徽省农业农村厅现代农业产业技术体系项目(AHCYJSTX-07);安徽科技学院校级稳定人才项目(dkwd201702);安徽科技学院兽医学校级高峰学科项目(XK-XJGF002)。

摘　　要：口腔毛滴虫是寄生于人和动物口腔中的一种人兽共患鞭毛原虫,与人和动物牙周病密切相关,而牙周病是人和动物最常见的炎症性疾病之一。口腔毛滴虫可对哺乳动物细胞造成损伤并分泌半胱氨酸等毒性蛋白,但该虫的致病性尚未完全清楚。近年来,全球人和犬等动物口腔毛滴虫的流行报道日益增多,做好该虫的流行病学调查及阐明其致病机理对于有效控制和预防牙周病至关重要。论文全面回顾了口腔毛滴虫的历史、病原形态、致病性、流行病学、诊断、控制和预防等方面的进展,以期引起专家和公众对这一长期被忽视的人兽共患原虫的关注。未来需要对不同宿主的口腔毛滴虫感染进行更多的流行病学和临床研究,以便更好地了解其致病性,进而开发有效药物控制该原虫,减少全球牙周病的流行。Trichomonas tenax is a flagellated zoonotic protozoan identified in the oral cavities of humans and animals,and has been associated with periodontal disease,which is the most prevalent inflammatory disease affecting humans and animals in the world.T.tenax can cause damage to mammalian cells and secretes virulent proteins,such as cysteine,but the pathogenicity of this oral protozoan still remains unclear.Because of its increasing prevalence in both humans and dogs in the world,detecting and elucidating the pathogenicity of this protozoan is very important for effective global control and prevention of periodontal disease.Here,we comprehensively review the history,morphology,pathogenicity,prevalence,diagnosis,control and prevention of T.tenax,and hopefully this article will draw attention to both medical and veterinary experts and the public on this neglected zoonotic parasite.In the future,more epidemiological and clinical studies need to be done on T.tenax to gain a better understanding of its pathogenicity,develop effective drugs to control this oral parasite,and reduce the spread of periodontal disease worldwide.

关 键 词：口腔毛滴虫 牙周炎 人兽共患 

分 类 号：S852.722[农业科学—基础兽医学] S855.99[农业科学—兽医学]