药食同源补气药防治慢性疲劳综合征机制研究进展  

Research Progress on Mechanism of Mecicinal and Edible Qi Tonifying Herbs in Prevention and Treatment of Chronic Fatigue Syndrome

作　　者：曹艳 饶佳丽 卢闵 陈明 CAO Yan;RAO Jia-li;LU Min;CHEN Ming(College of Pharmacy,Hubei University of Chinese Medicine,Wuhan 430065,China)

机构地区：[1]湖北中医药大学药学院,湖北武汉430065

出　　处：《食品与药品》2024年第5期I0006-I0011,共6页Food and Drug

基　　金：2023年全国中药特色技术传承人才培训项目(编号:T20234832005)。

摘　　要：慢性疲劳综合征(chronic fatigue syndrome,CFS)是一种原因不明的反复发作的疾病,以严重疲劳为基本特征,常伴随有认知功能障碍、睡眠问题、自主神经功能障碍和疼痛。CFS发病率上升,研究CFS的发病机制以及开发安全有效的治疗药物显得格外重要。药食同源补气药能有效改善CFS,可用于开发防治CFS且可长期使用的功能性食品。本文综述了抗CFS药食同源类补气药的研究现状、CFS病理机制、药食同源补气药防治CFS作用机制,并重点介绍了人参、党参、黄芪和西洋参等4种具有代表性的药食同源类补气药及其抗疲劳作用,为其临床应用提供理论依据,以期为相关功能性食品的开发提供参考。Chronic fatigue syndrome(CFS)is a recurrent disease of unknown cause characterized by severe fatigue.It is often associated with cognitive impairment,sleep problems,autonomic dysfunction and pain.The incidence of CFS is on the rise,and it is important to study the pathogenesis of CFS and develop safe and effective therapeutic drugs.Medicinal and edible Qi tonifying herbs can effectively improve CFS,thus can be utilized to develop functional foods for the prevention and treatment of CFS that can be used for a long time.This article reviews the research status of anti-CFS medicinal and edible Qi tonifying herbs,the pathological mechanism of CFS,and the mechanism of medicinal and edible Qi tonifying herbs for prevention and treatment of CFS.The four medicinal and edible Qi tonifying herbs including Ginseng Radix et Rhizoma,Codonopsis Radix,Astragali Radix and Panacis Quinquefolii Radix and their anti-fatigue effects are highlighted in this paper,so as to provide the theoretical basis for their clinical application and reference for the development of related functional foods.

关 键 词：药食同源 慢性疲劳综合征 人参 党参 黄芪 西洋参 

分 类 号：R287[医药卫生—中药学] R247.1[医药卫生—中医学]