神经外科静脉血栓相关治疗进展  

Advances in the treatment of venous thromboembolism in the neurosurgery department

作　　者：泮旭峰 吴蓉 柴海飞[1] 汪杰[1] 胡小铭[1] Pan Xufeng;Wu Rong;Chai Haifei;Wang Jie;Hu Xiaoming(Department of Neurosurgery,Taizhou Hospital of Zhejiang Province,Taizhou 317000,Zhejiang Province,China;Department of Internal Medicine,Linhai First People's Hospital,Linhai 317000,China)

机构地区：[1]浙江省台州医院神经外科,台州317000 [2]临海市第一人民医院内科,临海317000

出　　处：《中国基层医药》2024年第9期1433-1436,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省台州市科技局B类科技计划(20ywb15)。

摘　　要：静脉血栓在神经外科的治疗中是一类常见的伴随疾病,可导致致死性肺栓塞危及患者的生命健康。由于神经外科疾病的特殊性,通常伴随高危的出血风险,与静脉血栓的治疗背道而驰。虽然目前已有大量的观察性研究及Meta分析支持创伤性脑损伤及脑出血等颅内出血性疾病在出血稳定后早期启动抗凝预防或治疗的可行性,但缺乏高质量临床研究,因此目前神经外科医师在静脉血栓的药物预防及抗凝治疗方面仍偏保守。静脉血栓预防治疗时机、监测及何时停用等情况仍需高质量研究来确定。Venous thromboembolism is a common comorbidity in neurosurgery department that can lead to life-threatening pulmonary embolism,endangering patient health.The unique characteristics of neurosurgical conditions often present a high risk of bleeding,which complicates the treatment of venous thrombosis.Although numerous observational studies and meta-analyses support the feasibility of initiating early anticoagulation prevention or treatment after hemorrhage stabilization in intracranial hemorrhagic conditions such as traumatic brain injury and cerebral hemorrhage,there is a lack of high-quality clinical research.As a result,neurosurgeons tend to adopt a conservative approach regarding pharmacological prophylaxis and anticoagulant treatment for venous thromboembolism.Key aspects such as the timing of prevention,monitoring,and discontinuation of treatment still require high-quality research to establish definitive guidelines.

关 键 词：静脉血栓栓塞 脑出血 脑肿瘤 创伤和损伤 抗凝药 肝素 低分子量 综述 

分 类 号：R651[医药卫生—外科学]