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作 者:孙程程 陈峰 张宇 Sun Chengcheng;Chen Feng;Zhang Yu(Wenzhou People’s Hospital,Wenzhou,Zhejiang 325000,China)
出 处:《首都食品与医药》2024年第19期49-52,共4页Capital Food Medicine
摘 要:目的研究单胎与多胎早产儿生后生长发育情况,为多胎早产儿体格发育提供参考依据。方法回顾性分析2017年1月-2021年1月在温州市人民医院儿童保健科门诊随访的单胎、多胎早产儿的临床资料。结果研究期间能够完成定期随访至纠正月龄24月的早产儿有341例,单胎早产儿225例(66.0%),多胎早产儿116例(34.0%)。多胎早产儿剖宫产率高于单胎早产儿,分别为95.7%、46.7%。多胎早产儿生后小于胎龄儿比例更高,出生时体重更轻、身长更矮(P<0.05)。新生儿期间,多胎早产儿发生新生儿败血症比例高于单胎早产儿,分别为2.6%、0%;而其发生新生儿高胆红素血症比例低于单胎早产儿,分别为1.7%、15.6%。多胎早产儿在生后各时间段(纠正月龄6月、12月、18月、24月)生长发育状况与单胎早产儿无统计学差异(P>0.05)。结论多胎早产儿生后新生儿败血症发生率高于单胎早产儿,而新生儿高胆红素血症发生率低于单胎早产儿。出生时多胎早产儿体格发育落后于单胎早产儿,生后两者生长发育状况无明显差异。Objective To study the postnatal growth and development of single and multiple preterm infants,and provide reference for the growth and development of multiple preterm infants.Methods The clinical data of single and multiple preterm infants who were followed up in the outpatient department of children’s health care of our hospital from January 2017 to January 2021 were analyzed retrospectively.Results During the study period,341 preterm infants were able to complete regular follow-up to 24 months of corrected age,225 single preterm infants(66.0%)and 116 multiple preterm infants(34.0%).The cesarean section rate of multiple premature infants was 95.7%and 46.7%higher than that of single premature infants.The proportion of multiparous premature infants born smaller than gestational age was higher,and they were lighter and shorter at birth(P<0.05).During the neonatal period,the incidence of neonatal sepsis in multiple premature infants was higher than that in single premature infants,at 2.6%and 0%,respectively;the incidence of neonatal hyperbilirubinemia was 1.7%and 15.6%lower than that of single preterm infants.There was no significant difference between the growth and development of multiple preterm infants and single preterm infants at various time points after birth(6 months,12 months,18 months,24 months of corrected age)(P>0.05).Conclusion The incidence of neonatal sepsis in multiple preterm infants is higher than that in single preterm infants,while the incidence of neonatal hyperbilirubinemia is lower than that in single preterm infants.At birth,the physical development of multiple preterm infants lagged behind that of single preterm infants,and there was no significant difference in their growth and development after birth.
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