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作 者:高圆圆 刘佳佳 卢秋生 高明霞[2] GAO Yuan-yuan;LIU Jia-jia;LU Qiu-sheng;GAO Ming-xia(The First Clinical Medical College of Lanzhou University,Lanzhou 730000;Reproductive Medicine Center,The First Hospital of Lanzhou University,Lanzhou 730000)
机构地区:[1]兰州大学第一临床医学院,兰州730000 [2]兰州大学第一医院生殖医学中心,兰州730000
出 处:《生殖医学杂志》2024年第10期1401-1406,共6页Journal of Reproductive Medicine
基 金:2024年甘肃省海智计划项目(GSHZSF2024-08);甘肃省高校科研创新平台重大培育项目(2024CXPT-16)。
摘 要:子宫和卵巢作为女性生殖系统的核心组成部分,其功能的正常发挥对于女性的生育能力至关重要。然而,多种因素如衰老、疾病、损伤等均可导致子宫和卵巢功能的减退或丧失,进而影响女性的生育健康。因此,寻找有效的治疗策略以恢复或增强子宫和卵巢的功能成为当前研究的热点。干细胞作为再生医学领域的一种前沿治疗手段,因其具有多向分化的特性,在恢复女性生育能力方面显示出巨大的应用前景。然而,虽然有关干细胞的研究不断增加,但是关于其在子宫和卵巢生殖功能方面应用的系统性综述和研究相对较少,因此本文综述了干细胞在子宫和卵巢生殖功能方面的研究进展及其应用潜力。The uterus and ovaries are the core components of the female reproductive system,and their normal functions are crucial to female fertility.However,various factors such as aging,disease,injury,etc.can cause the decline or loss of uterine and ovarian functions,thereby affecting women’s reproductive health.Therefore,the development of effective treatment strategies to restore or enhance ovarian and uterine function has become a current research hotspot.As a cutting-edge treatment method in the field of regenerative medicine,the application of stem cells shows great application prospects in restoring female fertility due to their multi-directional differentiation characteristics.However,although research on stem cells continues to increase,there are relatively few systematic reviews and studies on their application in uterine and ovarian reproductive functions.Therefore,this article aims to comprehensively review the research and application progress of stem cells in the reproductive functions of the uterus and ovaries.
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