Possible viral agents to consider in the differential diagnosis of blepharoconjunctivitis  

作　　者：Mutali Musa Babatunde Ismail Bale Ayuba Suleman Gladness Aluyi-Osa Ekele Chukwuyem FabianaD’Esposito Caterina Gagliano Antonio Longo Andrea Russo Marco Zeppieri 

机构地区：[1]Department of Optometry,University of Benin,Benin 300283,Nigeria [2]Department of Ophthalmology,Africa Eye Laser Centre Ltd,Benin 300105,Nigeria [3]Department of Ophthalmology,Centre for Sight Africa Ltd,Nkpor 434212,Nigeria [4]Imperial College Ophthalmic Research Group Unit,Imperial College,London NW15QH,United Kingdom [5]GENOFTA srl,Via A.Balsamo,93,Naples 80065,Italy [6]Department of Medicine and Surgery,University of Enna"Kore",Catania 94100,Italy [7]Eye Clinic,Catania University San Marco Hospital,Catania 95121,Italy [8]Department of Ophthalmology,University Hospital of Catania,Catania 95123,Italy [9]Department of Ophthalmology,University Hospital of Udine,Udine 33100,Italy

出　　处：《World Journal of Virology》2024年第4期120-134,共15页世界病毒学杂志（英文）

摘　　要：BACKGROUND Blepharoconjunctivitis poses a diagnostic challenge due to its diverse etiology,including viral infections.Blepharoconjunctivits can be acute or chronic,selflimiting,or needing medical therapy.AIM To review possible viral agents crucial for accurate differential diagnosis in cases of blepharoconjunctivitis.METHODS The PubMed database was searched for records relating to viral blepharoconjunctivitis.The search string generated was“("virally"[All Fields]OR"virals"[All Fields]OR"virology"[MeSH Terms]OR"virology"[All Fields]OR"viral"[All Fields])AND"Blepharoconjunctivitis"[All Fields]".RESULTS A total of 24 publications were generated from the search string.Reference lists from each relevant article were also searched for more information and included in this review.Viral etiologies such as adenovirus,herpes simplex virus(HSV),varicella-zoster virus(VZV),and Epstein-Barr virus(EBV)are frequently implicated.Adenoviral infections manifest with follicular conjunctivitis and preauricular lymphadenopathy,often presenting as epidemic keratoconjunctivitis.HSV and VZV infections can result in herpetic keratitis and may exhibit characteristic dendritic corneal ulcers.EBV,although less common,can cause unilateral or bilateral follicular conjunctivitis,particularly in immunocompromised individuals.Other potential viral agents,such as enteroviruses and molluscum contagiosum virus,should also be considered,especially in pediatric cases.CONCLUSION Prompt recognition of these viral etiologies is essential for appropriate management and prevention of complications.Thus,a thorough understanding of the clinical presentation,epidemiology,and diagnostic modalities is crucial for accurate identification and management of viral blepharoconjunctivitis.

关 键 词：VIRAL Blepharoconjunctivitis Herpes simplex virus VARICELLA-ZOSTER EPSTEIN-BARR 

分 类 号：R373[医药卫生—病原生物学]