Targeting neuronal PAS domain protein 2 and KN motif/ankyrin repeat domains 1:Advances in type 2 diabetes therapy  

作　　者：Chun-Han Cheng Wen-Rui Hao Tzu-Hurng Cheng 

机构地区：[1]Department of Medical Education,Linkou Chang Gung Memorial Hospital,Taoyuan 33305,Taiwan [2]Division of Cardiology,Department of Internal Medicine,Shuang Ho Hospital,Ministry of Health and Welfare,Taipei Medical University,New Taipei 23561,Taiwan [3]Division of Cardiology,Department of Internal Medicine,School of Medicine,College of Medicine,Taipei Medical University,Taipei 11002,Taiwan [4]Department of Biochemistry,School of Medicine,College of Medicine,China Medical University,Taichung 404328,Taiwan

出　　处：《World Journal of Diabetes》2024年第11期2173-2176,共4页世界糖尿病杂志（英文）

摘　　要：This editorial summarizes the latest literature on the roles of neuronal PAS domain protein 2 and KN motif/ankyrin repeat domain 1 in type 2 diabetes(T2D).We highlight their involvement inβ-cell dysfunction,explore their potential as therapeutic targets,and discuss the implications for new treatment strategies.We offer valuable insights into relevant gene regulation and cellular mechanisms relevant for the targeted management of T2D.

关 键 词：Type 2 diabetes Neuronal PAS domain protein 2 KN motif and ankyrin repeat domain 1 β-cell dysfunction Therapeutic target 

分 类 号：R587.1[医药卫生—内分泌]