Leukopenia-a rare complication secondary to invasive liver abscess syndrome in a patient with diabetes mellitus:A case report  

作　　者：Chun-Yan Niu Bang-Tao Yao Hua-Yi Tao Xin-Gui Peng Qing-Hua Zhang Yue Chen Lu Liu 

机构地区：[1]Department of Gastroenterology,Nanjing Lishui People’s Hospital,Zhongda Hospital Lishui Branch,Southeast University,Nanjing 211200,Jiangsu Province,China [2]Department of Ophthalmology,Nanjing Lishui People’s Hospital,Nanjing 211200,Jiangsu Province,China [3]Department of Medical Imaging,Nanjing Lishui People’s Hospital,Zhongda Hospital Lishui Branch,Southeast University,Nanjing 210009,Jiangsu Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第10期3343-3349,共7页世界胃肠外科杂志（英文）

基　　金：Supported by the 2022 Nanjing Health Science and Technology Development Special Fund Support Project,No.YKK22240.

摘　　要：BACKGROUND Thrombocytopenia is a common complication of invasive liver abscess syndrome(ILAS)by Klebsiella pneumoniae(K.pneumoniae)infection,which indicates severe infection and a poor prognosis.However,the presence of leukopenia is rare.There are rare reports on leukopenia and its clinical significance for ILAS,and there is currently no recognized treatment plan.Early and broad-spectrum antimi-crobial therapy may be an effective therapy for treating ILAS and improving its prognosis.CASE SUMMARY A 55-year-old male patient who developed fever,chills,and abdominal distension without an obvious cause presented to the hospital for treatment.Laboratory tests revealed thrombocytopenia,leukopenia,and multiple organ dysfunction.Imaging examinations revealed an abscess in the right lobe of the liver and thromboph-lebitis,and K.pneumoniae was detected in the blood cultures.Since the patient was diabetic and had multi-system involvement,he was diagnosed with ILAS accom-panied by leukopenia and thrombocytopenia.After antibiotic treatment and sys-temic supportive therapy,the symptoms disappeared,and the patient’s condition almost completely resolved.CONCLUSION Leukopenia is a rare complication of ILAS,which serves as an indicator of adverse prognostic outcomes and the severity of infection.

关 键 词：Invasive liver abscess syndrome Klebsiella pneumoniae LEUKOPENIA THROMBOCYTOPENIA Treatment Prognosis Case report 

分 类 号：R657.3[医药卫生—外科学]