Hyperparathyroidism presented as multiple pulmonary nodules in hemodialysis patient status post parathyroidectomy:A case report  

作　　者：Ping-Han Chiang Kai-Hsiung Ko Yi-Jen Peng Tsai-Wang Huang Shih-En Tang 

机构地区：[1]Department of Surgery,Tri-Service General Hospital,Taipei 114202,Taiwan [2]Department of Radiology,National Defense Medical Center,Tri-Service General Hospital,Taipei 114,Taiwan [3]Department of Pathology,Tri-Service General Hospital,National Defense Medical Center,Taipei 114,Taiwan [4]Division of Thoracic Surgery,Department of Surgery,Tri-Service General Hospital,National Defense Medical Center,Taipei 114202,Taiwan [5]Division of Thoracic Medicine,Department of Internal Medicine,Tri-Service General Hospital,Taipei 114202,Taiwan

出　　处：《World Journal of Radiology》2024年第9期466-472,共7页世界放射学杂志（英文）

摘　　要：BACKGROUND Primary hyperparathyroidism is typically caused by a single parathyroid adenoma.Ectopic parathyroid adenomas occur as well,with cases involving various sites,including the mediastinum,presenting in varying frequencies.Secondary hyperparathyroidism develops in the context of chronic kidney disease,primarily due to vitamin D deficiency,hypocalcemia,and hyperphosphatemia.It is frequently diagnosed in patients undergoing dialysis.This article presents a rare case of hyperparathyroidism involving multiple hyperplastic parathyroid glands with pulmonary seeding in a 50-year-old female patient undergoing hemodialysis(HD).CASE SUMMARY The patient had a history of parathyroidectomy 10 years prior but developed recurrent hyperparathyroidism with symptoms of pruritus and cough with sputum during a period of routine dialysis.Radiographic imaging revealed multiple nodules in both lungs,with the largest measuring approximately 1.35 cm.Surgical histopathology confirmed the presence of hyperplastic parathyroid glands within the pulmonary tissue.After tumor resection surgery via videoassisted thoracic surgery with wedge resection,the patient was discharged in stable condition and in follow-up her symptoms showed improvement.CONCLUSION This article describes hyperparathyroidism presenting as pulmonary nodules in a patient undergoing postparathyroidectomy HD,highlighting diagnostic challenges and a positive outcome from tumor resection surgery.

关 键 词：HYPERTENSION End-stage renal disease HYPERPARATHYROIDISM Pulmonary nodules HEMODIALYSIS Video-assisted thoracic surgery Hyperplastic parathyroid glands Case report 

分 类 号：R521[医药卫生—内科学] R581[医药卫生—临床医学]