地奈德乳膏联合禾零润肤霜治疗婴幼儿轻中度特应性皮炎的临床疗效  

Clinical efficacy of desonide cream combined with Heling emollient in treatment of mild to moderate atopic dermatitis in infants

作　　者：曹玉婷 李金梅 CAO Yuting;LI Jinmei(Department of Dermatology,Inner Mongolia Maternal and Child Health Hospital,Hohhot 010052,China)

机构地区：[1]内蒙古自治区妇幼保健院,内蒙古呼和浩特010052

出　　处：《包头医学院学报》2024年第10期43-45,59,共4页Journal of Baotou Medical College

摘　　要：目的:探讨地奈德乳膏联合禾零润肤霜治疗婴幼儿轻中度特应性皮炎的疗效和安全性。方法:选取内蒙古自治区妇幼保健院皮肤科2022年6月至2023年6月收治的60例患有轻中度特应性皮炎的婴幼儿,根据随机数字表法分为对照组和观察组各30例,对照组单独外用地奈德乳膏治疗,观察组采用地奈德乳膏联合禾零润肤霜治疗,对比两组患儿治疗前后的特应性皮炎评分(scoring atopic dermatitis,SCORAD)及临床疗效。结果:经治疗2周后,两组患儿SCORAD评分和临床疗效均有改善,观察组SCORAD评分和有效率均优于对照组(P<0.05);观察组不良反应发生率为3.33%,对照组为16.66%(P>0.05)。结论:地奈德乳膏联合禾零润肤霜治疗轻中度特应性皮炎患儿,能够显著减轻临床症状,提高治疗效果。Objective:To investigate the efficacy of desonide cream combined with Heling emollient in the treatment of mild to moderate atopic dermatitis in infants.Methods:A total of 60 infants with atopic dermatitis treated in our hospital from June 2022 to June 2023 were randomly divided into the control group(n=30)and the observation group(n=30).The control group was treated with desonide cream alone,the observation group was treated with desonide cream combined with Heling emollient.Scoring atopic dermatitis(SCORAD)before and after treatment and the clinical efficacy were compared between the two groups of patients.Results:After 2 weeks of treatment,the SCORAD scores and clinical efficacy of two groups were both improved,and the SCORAD score and effective rate in the observation group were better than those in the control group(P<0.05).The incidence rate of adverse reactions in the observation group and the control group was 3.33%and 16.66%respectively(P>0.05).Conclusion:Desonide cream combined with Heling emollient can significantly reduce clinical symptoms and improve the therapeutic effect in infants with mild to moderate atopic dermatitis.

关 键 词：地奈德乳膏 禾零润肤霜 婴幼儿 轻中度特应性皮炎 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]