地黄的主要化学成分及药理作用研究进展  

Research progress on the main chemical constituents and pharmacological actions of Rehmannia glutinosa

作　　者：张紫怡 张来宾[1] 吕洁丽[1] ZHANG Ziyi;ZHANG Laibin;LYU Jieli(College of Pharmacy,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)

机构地区：[1]新乡医学院药学院,河南新乡453003

出　　处：《新乡医学院学报》2024年第10期979-986,共8页Journal of Xinxiang Medical University

基　　金：国家自然科学基金项目(编号:81773898);河南省优秀青年科学基金项目(编号:212300410066);河南省科技攻关项目(编号:242102310506)。

摘　　要：地黄为玄参科地黄属植物,是我国药食同源常用中药材之一,始载于《神农本草经》,临床应用广泛,主产于河南、河北、山东、山西等地,以河南怀庆府产最为道地,是著名的“四大怀药”之一。近年来,随着国内外学者对地黄全面深入地研究,其结构多样的化学成分、广泛的药理作用及开发应用备受关注。本文对地黄化学成分和药理活性的相关文献进行综述,旨在为相关研究提供参考。Rehmannia glutinosa,belonging to the genus Rehmannia(family Scrophulariaceae),is a widely used Chinese medical herb that is included in the list of medicine and food homology substances in China.First described in Shennong′s Classic of Materia Medica,it has been widely used clinically now.Mainly produced in Henan,Hebei,Shandong and Shanxi,the Rehmannia glutinosa in Huaiqing Prefecture(an ancient administrative district)of Henan is the most authentic,and it is listed as one of the four famous Chinese herbs produced in the Huaiqing area.In recent years,with the comprehensive and in-depth study of Rehmannia glutinosa by scholars at home and abroad,its diverse chemical constituents,extensive pharmacological actions,development and application have attracted much attention.In this paper,the relevant literature on the main chemical constituents and pharmacological activities of Rehmannia glutinosa is reviewed,in order to provide references for related research.

关 键 词：地黄 化学成分 环烯醚萜 药理作用 

分 类 号：R285[医药卫生—中药学]