人工胰腺治疗儿童1型糖尿病的应用现状  

Application of artificial pancreas in treatment of type 1 diabetes mellitus in children

作　　者：杨立红 徐海 韩林岐 魏志强 孙妍 Yang Lihong;Xu Hai;Han Linqi;Wei Zhiqiang;Sun Yan(Department of Pediatrics,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250021,China;Department of Pediatrics,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China;School of Clinical Medicine,Shandong Second Medical University,Weifang 261053,China;Pediatrics of Traditional Chinese Medicine,College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东第一医科大学(山东省医学科学院)儿科学,济南250021 [2]山东第一医科大学附属省立医院儿科,济南250021 [3]山东第二医科大学临床医学院,潍坊261053 [4]山东中医药大学中医儿科学,济南250355

出　　处：《中华实用儿科临床杂志》2024年第10期789-792,共4页Chinese Journal of Applied Clinical Pediatrics

基　　金：山东省自然科学基金面上项目(ZR2020MH003);山东省中医药科技面上项目(M-2022203)。

摘　　要：1型糖尿病(T1DM)是儿童糖尿病的主要类型,严重危害儿童健康。随着科技的发展,人工胰腺的出现为T1DM的治疗带来了新的曙光。人工胰腺是通过连续血糖监测、控制算法精准调控胰岛素泵输注,模拟人体胰腺β细胞胰岛素的生理分泌来控制血糖、实现闭环管理。现就人工胰腺目前应用的安全性、有效性、局限性进行综述,以期为T1DM儿童的治疗提供与时俱进的选择。Type 1 diabetes mellitus(T1DM)is the main type of diabetes in children,which seriously endangers children′s health.With the development of technology,the emergence of artificial pancreas has brought new progress for the treatment of T1DM.Artificial pancreas can imitate the insulin physiological secretion of pancreasβcells to control glucose,and achieve close-loop management by accurately regulating insulin infusion through continuous glucose monitoring,insulin pump and control algorithms.Here the current clinical studies on the safety,effectiveness and limitations of artificial pancreas in the treatment of T1DM were reviewed.It is expected to provide another choice for children with T1DM.

关 键 词：1型糖尿病 儿童 人工胰腺 

分 类 号：R725.8[医药卫生—儿科]