1例接种脊髓灰质炎灭活疫苗发生皮肤硬结的案例分析  

Analysis of One Case with Skin Induration After Inoculating Polio Inactivated Vaccine

作　　者：李伟健 王敏 李海香 张复臣[1] Li Weijian;Wang Min;Li Haixiang;Zhang Fuchen(Heze Center for Disease Control and Prevention,Heze 274010,Shandong Province,China;Heze City Juye County Center for Disease Control and Prevention,Juye 274000,Shandong Province,China)

机构地区：[1]菏泽市疾病预防控制中心,山东菏泽274010 [2]菏泽市巨野县疾病预防控制中心,山东巨野274000

出　　处：《中国社区医师》2024年第26期136-138,共3页Chinese Community Doctors

摘　　要：脊髓灰质炎是由脊髓灰质炎病毒感染引起的以肢体麻痹为主要表现的急性肠道传染疾病,病毒常侵袭神经系统,可造成机能完全瘫痪,好发于儿童。目前脊髓灰质炎无特效治疗方法,接种疫苗是预防脊髓灰质炎病毒传播最经济、最有效的方法。但接种脊髓灰质炎灭活疫苗后,极少部分患者会出现恶心、呕吐、发热、皮疹、紫癜等不良反应,因此在进行接种时应该加强对不良反应的监测。该文对菏泽市1例接种脊髓灰质炎灭活疫苗后发生皮肤硬结的案例进行分析,为疑似疫苗预防接种异常反应与偶合症的监测、调查、诊断、处置提供科学依据,以期最大程度地避免疑似疫苗预防接种异常反应与偶合症的发生。Poliomyelitis is an acute intestinal infectious disease caused by poliovirus infection with limb paralysis as the main manifestation,and the virus often invades the nervous system,can causes complete paralysis of the function,and often occurs in children.At present,there is no specific treatment for poliomyelitis,and vaccination is the most economical and effective way to prevent the spread of poliovirus.However,after receiving inactivated polio vaccine,a very small number of patients may have adverse reactions such as nausea,vomiting,fever,rash and purpura,so the monitoring of adverse reactions should be strengthened during vaccination.This paper analyzes one case with skin induration after inoculating polio inactivated vaccine in Heze City,so as to provide a scientific basis for the monitoring,investigation,diagnosis and treatment of suspected vaccination abnormal reactions and coincidental diseases,thus minimizing the occurrence of suspected vaccination abnormal reactions and coincidental diseases.

关 键 词：脊髓灰质炎灭活疫苗 疫苗接种 皮肤硬结 

分 类 号：R186[医药卫生—流行病学]