PPH联合聚多卡醇泡沫硬化剂注射治疗直肠黏膜脱垂中的应用  

Application of PPH combined with polydocanol foam sclerosing agent injection in treatment of rectal mucosal prolapse

作　　者：李飞[1] 辛振 郭涛 吕振周 王富豪 Li Fei;Xin Zhen;Guo Tao;Lv Zhenzhou;Wang Fuhao(Department of Gastrointestinal Surgery,Huaibei Miners General Hospital,Huaibei,Anhui 235000,China)

机构地区：[1]淮北矿工总医院胃肠外科,安徽淮北235000

出　　处：《齐齐哈尔医学院学报》2024年第19期1822-1824,共3页Journal of Qiqihar Medical University

基　　金：徐州医科大学附属医院发展基金(XYFZ202301)。

摘　　要：目的探索PPH联合泡沫硬化剂在直肠黏膜脱垂新的治疗方法,为疾病治疗方式的选择提供参照。方法回顾性分析2023年4月—2024年4月在本院接受手术治疗直肠黏膜脱垂的86例患者的临床资料。根据患者手术方式不同分为观察组和对照组两组,观察组44例患者采用PPH联合聚多卡醇硬化剂注射治疗;对照组42例患者采用PPH治疗。分析两组患者便秘改善程度、临床治愈率和并发症等指标。结果两组患者在治疗前CAS、PAC-SYM、SAS和SDS比较,差异无统计学意义(P>0.05),两组患者在治疗后CAS、PAC-SYM、SAS和SDS均较治疗显著降低,差异均具有统计学意义(P<0.01)。但观察组在CAS、PAC-SYM、SAS和SDS治疗后降低程度高于对照组,差异具有统计学差异(P<0.05)。两组患者有效率比较,差异无统计学意义(44/0比41/1,χ^(2)=1.060,P=0.303)。但观察组治愈率显著高于对照组,差异具有统计学意义(42/2比33/9,χ^(2)=5.491,P=0.019)。两组患者在的短、长期并发症、术后疼痛和术后炎症指标的比较,差异均无统计学意义(P>0.05)。结论PPH联合聚多卡醇硬化剂注射治疗对治疗直肠黏膜脱垂效果显著,可增加临床治愈率,是一种安全有效的治疗方法。Objective To explore a new therapeutic method for rectal mucosal prolapse using PPH combined with polydocanol foam sclerosing agent,providing a reference for the selection of disease treatment methods.Methods Clinical data of 86 patients who underwent surgical treatment for rectal mucosal prolapse at our hospital from April 2023 to April 2024 were included.Patients were divided into an observation group and a control group based on different surgical methods.The observation group(n=44)was treated with PPH combined with polydocanol sclerosing agent injection;the control group(n=42)received PPH treatment only.Indicators such as improvement in constipation,clinical cure rate,and complications were analyzed for both groups.Results There were no significant differences in CAS,PAC-SYM,SAS,and SDS scores between the two groups before treatment(P>0.05).After treatment,these scores were significantly reduced in both groups compared to pre-treatment values(P<0.01).However,the observation group showed a greater reduction in CAS,PAC-SYM,SAS,and SDS scores after treatment compared to the control group,with statistically significant differences(P<0.05).The efficacy rate comparison between the two groups showed no statistical significance(44/0 vs.41/1,χ^(2)=1.060,P=0.303).The cure rate was significantly higher in the observation group(42/2 vs.33/9,χ^(2)=5.491,P=0.019)than in the control group.There were no significant differences in short-term and long-term complications,postoperative pain,and postoperative inflammation indicators between the two groups(P>0.05).Conclusions The combination of PPH and polydocanol foam sclerosing agent injection is effective in treating rectal mucosal prolapse,increasing the clinical cure rate,and is a safe and effective treatment method.

关 键 词：直肠黏膜脱垂 吻合器直肠黏膜环切术 聚多卡醇 便秘 

分 类 号：R657.1[医药卫生—外科学]