Preparation of TiO_(2) Nano-Flower Coating on Ti Substrates with Good Physical Sterilization Effect and Biocompatibility  

作　　者：Ruoyu Di Yonghua Sun Runhua Yao Sen Pei Xiaohong Yao Ruiqiang Hang 

机构地区：[1]Shanxi Key Laboratory of Biomedical Metal Materials,College of Materials Science and Engineering,Taiyuan University of Technology,Taiyuan,030024,China [2]College of Safety and Emergency Management Engineering,Taiyuan University of Technology,Taiyuan,030024,China

出　　处：《Acta Metallurgica Sinica(English Letters)》2024年第9期1581-1589,共9页金属学报（英文版）

基　　金：jointly supported by the Four“Batches”Innovation Project of Invigorating Medical through Science and Technology of Shanxi Province(2022XM12);the Central Leading Science and Technology Development Foundation of Shanxi Province(YDZJSX2021A019);the Key Research and Development Program of Shanxi Province(202102130501007);the Natural Science Foundation of Shanxi Province(202103021223102,202203021222127).

摘　　要：We report a facile solution method to form titanium oxide(TiO_(2))nano-flower structure on the titanium(Ti)substrates for realizing good physical sterilization and biocompatibility.We first prepare TiO_(2) nanotubes(NT)with a diameter of about 80-100 nm and a length of about 5μm on Ti substrates by anodization,which is utilized as precursor.Then,we employ immersion treatment in different concentrations of phosphoric acid solution at 75℃ for 5 h to realize the transformation from TiO_(2) NT to TiO_(2) nano-flower structure.In addition,we studied the effects of phosphoric acid concentration(1 wt%,2.5 wt%,5 wt% and 10 wt%)on the TiO_(2) nano-flower structure,and the antibacterial properties and biocompatibility of the TiO_(2) nano-flower structure.The results show that TiO_(2) nano-flower structure become larger and thicker with the increase in the phosphoric acid concentration,and the thickness of the coating can reach 6.88μm.Meanwhile,the TiO_(2) nano-flower structure shows good physical sterilization effect,especially for the TiO_(2) nano-flower structure formed in 10 wt%H^(3)PO_(4) solution,the antibacterial rate can reach 95%.In addition,the TiO_(2) nano-flower structure have no toxicity to the osteoblasts and support cell growth.

关 键 词：Anodization BIOCOMPATIBILITY Physical sterilization TiO_(2)nano-flower 

分 类 号：TG17[金属学及工艺—金属表面处理]