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作 者:陈春艳[1,3] 张艳阳 王柱 CHEN Chunyan;ZHANG Yanyang;WANG Zhu(Department of Critical Care Medicine,Huangshi Central Hospital,Affiliated Hospital of Hubei Polytechnic University,Huangshi Hubei 435000;Department of Rehabilitation Medicine,Huangshi Central Hospital,Affiliated Hospital of Hubei Polytechnic University,Huangshi Hubei 435000;Hubei Key Laboratory of Kidney Diseases Pathogenesis and Intervention,Hubei Polytechnic University,Huangshi Hubei 435003)
机构地区:[1]黄石市中心医院(湖北理工学院附属医院)重症医学科,湖北黄石435000 [2]黄石市中心医院(湖北理工学院附属医院)康复医学科,湖北黄石435000 [3]湖北理工学院肾脏疾病发生与干预湖北省重点实验室,湖北黄石435003
出 处:《湖北理工学院学报》2024年第5期63-68,共6页Journal of Hubei Polytechnic University
基 金:湖北理工学院科研项目(项目编号:22xjz07Y)。
摘 要:为了探究BLUE-plus方案的肺超声评分引导胸部物理治疗(CPT)在急性呼吸衰竭患者氧合能力、感染指标和肺通气功能方面的效果,根据样本量估算招募急性呼吸衰竭患者102例,随机分为试验组和对照组。试验组根据BLUE-plus肺超声征象、肺超声评分实施精准CPT,对照组采用常规CPT。比较两组患者入ICU第1~5天的氧合指数和第1、5天的血感染指标(降钙素原(PCT)、白介素-6(IL-6))及肺部超声评分、机械通气时长和ICU住院时长,发现BLUE-plus方案的肺超声评分指导的CPT可以改善急性呼吸衰竭患者的氧合指数、感染指标(IL-6)、肺部情况,缩短机械通气的时间。相较于对照组,试验组在第3~5天的氧合指数具有统计学差异(P<0.05),第5天IL-6、肺部超声评分、机械通气时长差异具有统计学意义(P<0.05),PCT、ICU住院时长无统计学差异(P>0.05)。To explore the effects of pulmonary physical therapy(CPT)guided by BLUE-plus regimen and pulmonary ultrasound score on oxygenation,infection index and pulmonary ventilation function in patients with acute respiratory failure,102 patients with acute respiratory failure were recruited and randomly divided into test group and control group.The experimental group was treated with CPT according to BLUE-plus pulmonary ultrasonic signs and pulmonary ultrasonic score,while the control group was treated with routine CPT.The oxygenation index on day 1 to day 5 and blood infection index(Procalcitonin(PCT),Interleukin-6(IL-6)),lung ultrasonic score,duration of mechanical ventilation and length of ICU stay on day 1 and day 5 were compared between the two groups.CPT guided by lung ultrasound score combined with BLUE-plus regimen can improve oxygenation index,IL-6,lung condition and shorten the time of mechanical ventilation in patients with acute respiratory failure.Compared with the control group,there were significant differences in oxygenation index on day 3 to day 5(P<0.05),IL-6,lung ultrasound score and duration of mechanical ventilation on day 5(P<0.05),PCT and ICU length of stay had no significant difference(P>0.05).
关 键 词:BLUE-plus肺超声引导 急性呼吸衰竭 胸部物理治疗 氧合指数 肺超声评分
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