一种3-溴芴酮的合成工艺  

Synthesis Process of 3-Bromofluorone

作　　者：韩蒙蒙 马欣 李瑞 陈鹏丽[1] 李奎[1] 杨振强[1,2] 申奥 HAN Mengmeng;MA Xin;LI Rui;CHEN Pengli;LI Kui;YANG Zhenqiang;SHEN Ao(Henan Academy of Sciences Institute of Chemistry Co.,Ltd.,Zhengzhou 450002,China;Henan Kehua Environmental Materials Co.Ltd.,Qinyang 454550,China)

机构地区：[1]河南省科学院化学研究所有限公司,河南郑州450002 [2]河南科化环境材料有限公司,河南沁阳454550

出　　处：《化工技术与开发》2024年第10期11-13,22,共4页Technology & Development of Chemical Industry

基　　金：河南省科技研发计划联合基金资助项目(225200810094,225200810072);河南省科学院基本科研业务费项目(240603048);河南省科学院高水平成果奖励与培育项目(242203032);河南省科学平台补助项目(241003031)。

摘　　要：3-溴芴酮是制备有机电致发光材料、太阳能电池材料等功能性材料的重要中间体。本文以2-氨基芴为起始原料,经溴代反应、重氮化反应和氧化反应合成了3-溴芴酮产物。针对氧化过程中溶剂及碱的种类对收率的影响进行了优化选择。较佳的反应条件是:以四氢呋喃作为溶剂,氢氧化钾作为碱时,3-溴芴酮的收率较高,纯度达到99.9%,产品的质量好,生产成本较低,适合工业化生产。3-Bromofluorone was an important intermediate for the fabrication of functional materials such as organic electroluminescent materials and solar cell materials.In this article,2-aminofluorene was taken as the starting material,and the 3-bromofluorone was synthesized through bromination reaction,diazotization reaction and oxidation reaction.The impact of types of solvents and bases in the oxidation process on the yield was optimized and selected.The more favorable reaction conditions were:tetrahydrofuran as the solvent and potassium hydroxide as the base,under which the yield of 3-bromofluorone was relatively high,with a purity of 99.9%.The product quality was good and the production cost was relatively low,was suitable for industrial production.

关 键 词：2-氨基芴 3-溴芴酮 合成工艺 

分 类 号：TQ244.2[化学工程—有机化工]