左氧氟沙星联合金刚藤胶囊治疗慢性盆腔炎的临床疗效  

Clinical effiacay of levofloxacin combined with Jingangteng capsule in the treatment of chronic pelvic inflammation disease

作　　者：刁丽娜 孟君 刁希重 DIAO Li’na;MENG Jun;DIAO Xizhong(Department of Obstetrics and Gynecology,Longkou Hospital of Traditional Chinese Medicine,Yantai,Shandong,265701,China;Department of Pediatrics,Longkou Traditional Chinese Medicine Hospital,Yantai,Shandong,265701,China)

机构地区：[1]龙口市中医医院妇产科,山东烟台265701 [2]龙口市中医医院儿科,山东烟台265701

出　　处：《当代医学》2024年第15期21-25,共5页Contemporary Medicine

摘　　要：目的探讨左氧氟沙星联合金刚藤胶囊治疗慢性盆腔炎(CPID)的临床疗效。方法选取2021年1-12月龙口市中医医院妇产科收治的100例CPID患者作为研究对象,按照随机数字表法分为对照组与观察组,每组50例。对照组行左氧氟沙星治疗,观察组行左氧氟沙星联合金刚藤胶囊治疗。比较两组症状(腰骶酸痛、下腹疼痛、带下量多)评分、症状改善时间(下腹坠胀缓解时间、盆腔肿块消失时间、白带正常时间、腹痛缓解时间)、盆腔积液深度、包块直径、视觉模拟评分法(VAS)评分、血清炎症因子[降钙素原(PCT)、C反应蛋白(CRP)、WBC]、血液流变学指标[纤维蛋白原(Fg)、高切全血黏度、低切全血黏度]及临床疗效。结果治疗后,观察组腰骶酸痛、下腹疼痛、带下量多评分均低于对照组,差异有统计学意义(P<0.05)。观察组下腹坠胀缓解时间、盆腔肿块消失时间、白带正常时间、腹痛缓解时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,观察组盆腔积液深度浅于对照组,包块直径小于对照组,VAS评分低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组PCT、CRP、WBC水平均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组Fg、高切全血黏度、低切全血黏度水平均低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为94.00%,高于对照组的78.00%,差异有统计学意义(P<0.05)。结论左氧氟沙星联合金刚藤胶囊治疗CPID患者,能提高疗效,减少盆腔积液,缩小包块直径,尽快减轻患者临床症状及炎症状态,加快康复进程,缓解其疼痛感,改善血液流变学,值得临床推广应用。Objective To explore the clinical efficacy of levofloxacin combined with Jingangteng capsule in the treatment of chronic pelvic in-flammatory disease(CPID).Methods A total of 100 CPID patients admitted to the Obstetrics and Gynecology department of Longkou Chinese Med-icine Hospital from January to December 2021 were selected as the study subjects,and they were divided into the control group and the observation group by random number table method,with 50 cases in each group.The control group was treated with levofloxacin,and the observation group was treated with levofloxacin combined with Jingangteng capsule.The scores of symptom(lumbosacral pain,lower abdominal pain and heavy band vol-ume),symptom improvement time(lower abdominal distension relief time,pelvic mass disappearance time,normal leucorrhea time,abdominal pain relief time),pelvic effusion depth,mass diameter,visual analogue scale(VAS)score,serum inflammatory factors(procalcitonin[PCT],C-reactive protein[CRP],WBC),hemorheology index(fibrinogen[Fg],high shear rate whole blood viscosity and low hear rate whole blood viscosity)and clini-cal efficacy were compared between the two groups.Results After treatment,the symptom scores of lumbosacral pain,lower abdominal pain and heavy band volume in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The lower abdominal distention relief time,pelvic mass disappearance time,normal leucorrhea time and abdominal pain relief time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the pelvic effusion depth in the observation group was shallower than that in the control group,and mass diameter was smaller than that in the control group,and the VAS score was lower than that in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of PCT,CRP and WBC in the observation group were lower than those in the contr

关 键 词：左氧氟沙星 金刚藤胶囊 慢性盆腔炎 临床疗效 

分 类 号：R711.33[医药卫生—妇产科学]