经鼻持续气道正压通气联合多巴胺与多巴酚丁胺治疗婴幼儿重症肺炎的临床价值  

Clinical value of transnasal continuous positive airway pressure ventilation combined with dopamine and dobutamine in the treatment of infants and yang children with severe pneumonia

作　　者：丁云云 李燕燕[1] 张素云 DING Yunyun;LI Yanyan;ZHANG Suyun(Department of Pediatrics,The First People's Hospital of Fuzhou,Fuzhou,Jiangxi,344000,China)

机构地区：[1]抚州市第一人民医院儿科,江西抚州344000

出　　处：《当代医学》2024年第15期60-63,共4页Contemporary Medicine

摘　　要：目的探讨经鼻持续气道正压通气联合多巴胺、多巴酚丁胺治疗婴幼儿重症肺炎的临床价值。方法选取2020年1月至2022年7月抚州市第一人民医院收治的80例婴幼儿重症肺炎患儿作为研究对象,随机分为对照组与观察组,各40例。对照组采用经鼻持续气道正压通气疗法,观察组在对照组基础上联合多巴胺、多巴酚丁胺治疗,比较两组呼吸机应用时间、治疗5 d后心力衰竭发生率、临床疗效、症状体征恢复时间、心率、呼吸频率及肺功能指标。结果观察组呼吸机应用时间短于对照组,治疗5 d后心力衰竭发生率低于对照组,差异有统计学意义(P<0.05)。观察组临床病情控制优良率为95.00%,高于对照组的77.50%,差异有统计学意义(P<0.05)。观察组肺部湿啰音消失时间、三凹征消失时间、心率恢复正常时间、呼吸频率恢复正常时间均短于对照组,差异有统计学意义(P<0.05)。治疗5 d后,观察组心率、呼吸频率均慢于对照组,差异有统计学意义(P<0.05)。治疗5 d后,观察组FEV1、FVC、FEV1/FVC均大于对照组,差异有统计学意义(P<0.05)。结论将经鼻持续气道正压通气联合多巴胺与多巴酚丁胺疗法治疗婴幼儿重症肺炎效果显著,能缩短呼吸机应用时间及症状体征恢复时间,降低心力衰竭发生率,促进心率及呼吸频率恢复正常,改善患儿肺功能。Objective To investigate the clinical value of transnasal continuous positive airway pressure ventilation combined with dobutamine and dobutamine in infants and young children with severe pneumonia.Methods 80 infants and young children with severe pneumonia treated in Fuzhou First People's Hospital from January 2020 to July 2022 were selected as the research subjects,and they were randomly divided into the control group and the observation group,with 40 cases in each group.The control group was treated with transnasal continuous positive airway pressure ventilation therapy,the observation group was treated with dobutamine and dobutamine on the basis of the control group,the time of ventilator application,incidence of heart failure after 5 d of treatment,clinical efficacy,recovery time of symptoms and signs,heart rate and respiratory rate and lung function indexes were compared between the two groups.Results The time of ventilator application in the observation group was shorter than that in the control group,the incidence of heart failure after 5 d of treatment in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).The excellent and good rate of clinical disease control in the observation group was 95.00%,which was higher than 77.50%in the control group,and the difference was statistically significant(P<0.05).The disappearance time of lung moist rale,triple concave sign,heart rate return to normal,and respiratory rate return to normal in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After 5 d of treatment,the heart rate and respiratory rate in the observation group were slower than those in the control group,and the differences were statistically significant(P<0.05).After 5 d of treatment,the FEV1,FVC,and FEV1/FVC in the observation group were larger than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Transnasal cont

关 键 词：多巴胺 多巴酚丁胺 经鼻持续气道正压通气 婴幼儿重症肺炎 

分 类 号：R725.6[医药卫生—儿科]