门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常的临床疗效及对患者心功能的影响  

Clinical effcacy of potassium magnesium aspartate combined with amiodarone in the treatment of ventricular arrhythmia in acute myocardial infarction and its influence on cardiac function

作　　者：殷涛 索郢 李晓龙 贾书辉 石磊 YIN Tao;SUO Ying;LI Xiaolong;JIA Shuhui;SHI Lei(Department of Cardiology,Wuhai People's Hospital,Wuhai,Inner Mongolia,016000,China)

机构地区：[1]乌海市人民医院心内科,内蒙古乌海016000

出　　处：《当代医学》2024年第15期131-134,共4页Contemporary Medicine

摘　　要：目的探究门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常的临床疗效及对患者心功能的影响。方法回顾性分析2020年6月至2022年6月乌海市人民医院收治的78例急性心肌梗死室性心律失常患者的临床资料,根据不同的治疗方法分为对照组与观察组,每组39例。对照组在常规对症治疗的基础上接受胺碘酮治疗,观察组在对照组基础上接受门冬氨酸钾镁治疗。比较两组临床疗效、临床症状恢复时间及治疗前后心功能水平。结果观察组临床总有效率高于对照组,差异有统计学意义(P<0.05)。观察组胸痛症状消失时间、心率恢复正常时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,观察组左心室射血分数(LVEF)、左心室短袖缩短分数(FS)均高于对照组,左心室收缩末期内径(LVESD)、左心室舒张末期内径(LVEDD)均短于对照组,差异有统计学意义(P<0.05)。结论门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常效果显著,可改善患者心功能,快速缓解胸痛症状,恢复其心率水平。Objective To investigate the clinical efficacy of potassium magnesium aspartate combined with amiodarone in the treatment of ventricular arrhythmia in acute myocardial infarction and its influence on cardiac function.Methods The clinical data of 78 patients with acute myocardial infarction and ventricular arrhythmia admitted to Wuhai People's Hospital from June 2020 to June 2022 were retrospectively analyzed,they were divided into the control group and the observation group according to the different treatment methods,with 39 cases in each group.The control group received amiodarone treatment on the basis of conventional symptomatic treatment,while the observation group received potassium magnesium aspartate treatment on the basis of the control group.The clinical efficacy,recovery time of clinical symptoms and the level of cardiac function before and after treatment were compared between the two groups.Results The total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The disappearance time of chest pain symptoms and the recovery time of heart rate in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,left ventricular ejection fraction(LVEF)and left ventricular short sleeve shortening fraction(FS)in the observation group were higher than those in the control group,the left ventricular end systolic diameter(LVESD)and left ventricular end diastolic diameter(LVEDD)in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Potassium magnesium aspartate combined with amiodarone in the treatment of acute myocardial infarction ventricular arrhythmias has a significant effect,can improve the cardiac function of patients,rapidly relieve chest pain symptoms,restore heart rate level.

关 键 词：心功能 门冬氨酸钾镁 急性心肌梗死 胺碘酮 室性心律失常 胸痛 心率 临床疗效 

分 类 号：R542.22[医药卫生—心血管疾病]