中医伤科一号方治疗膝关节软组织损伤临床效果及其作用机制  

Clinical Effect and Mechanism of Shangke No.1 Formula(伤科一号方)Treating Patients with Soft Tissue Injury of Knee Joint

作　　者：李玉福 蒋臻 王小菲 高凯 郑伟[1] LI Yufu;JIANG Zhen;WANG Xiaofei;GAO Kai;ZHENG Wei(The Third Hospital of Shijiazhuang,Shijiazhuang 050000,Hebei,China)

机构地区：[1]石家庄市第三医院,河北石家庄050000

出　　处：《辽宁中医杂志》2024年第10期77-80,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(2022187)。

摘　　要：目的探讨中医伤科一号方治疗膝关节软组织损伤患者的临床效果及其作用机制。方法采取前瞻性随机临床试验,选取2021年9月—2022年11月医院收治的100例急性膝关节软组织损伤患者进行临床随机试验,采用随机数字表将患者分为伤科一号组和对照组各50例,两组的基础治疗为患肢制动、抬高患肢,伤科一号组在基础治疗上采用中医药方伤科一号治疗,对照组在基础治疗上采用予扶他林软膏治疗,疗程均为1周,对比治疗前后患者的临床症状评分、膝关节屈曲功能、膝关节周径及临床疗效的差异。结果治疗前,伤科一号组和对照组患者的膝关节肿胀、疼痛、压痛及功能障碍评分组间对比,差异无统计学意义(P>0.05);经过1周的治疗,两组患者的上述各项指标评分较本组治疗前均呈明显的下降趋势(P<0.05),伤科一号组患者的各项临床症状评分降低较对照组更为显著(P<0.05);治疗前,伤科一号组和对照组患者的膝关节屈曲功能、膝关节周径组间对比,差异无统计学意义(P>0.05);经过1周的治疗,两组患者的膝关节屈曲功能较本组治疗前均呈明显改善,膝关节周径测量值则明显降低(P<0.05),伤科一号组患者的膝关节屈曲功能优于对照组,膝关节周径测量值低于对照组(P<0.05)。经过1周的治疗,伤科一号组达到痊愈的有34例、好转的有16例,对照组痊愈24例、好转24例、无效2例,伤科一号组治疗效果优于对照组(P<0.05)。结论中医伤科一号方治疗膝关节软组织损伤患者能更有效地缓解患者的临床症状、改善膝关节功能恢复,提高临床疗效。Objective To investigate the clinical effect and mechanism of Shangke No.1 Formula(伤科一号方)in the treatment of patients with soft tissue injury of knee joint.Methods A prospective randomized clinical trial was conducted to select 100 patients with acute soft tissue injury of knee joint admitted to the hospital from September 2021 to November 2022 for clinical randomized trial.The patients were divided into the Shangke No.1 Formula group and the control group with 50 patients in each group using a random number table.The basic treatment of the two groups was to brake the affected limb and lift the affected limb.The Shangke No.1 Formula group was treated with Shangke No.1 Formula on the basis of the basic treatment.On the basis of basic treatment,the control group was treated with Voltalin Ointment for one week.The clinical symptom scores,knee flexion function,knee circumference and clinical efficacy of patients before and after treatment were compared.Results Before treatment,there was no significant difference in knee joint swelling,pain,tenderness or dysfunction scores between the Shangke No.1 Formula group and the control group(P>0.05).After one week of treatment,the scores of the above indexes of the patients in the two groups showed a significant downward trend compared with that before treatment(P<0.05),and the scores of the clinical symptoms of the patients in the Shangke No.1 Formula group decreased more significantly than those in the control group(P<0.05).Before treatment,there was no significant difference in knee flexion function or knee circumference between the Shangke No.1 Formula group and the control group(P>0.05).After one week treatment,the knee joint flexion function of the patients in both groups was significantly improved compared with that before treatment and the measured value of the knee joint circumference was significantly reduced(P<0.05).The knee joint flexion function of the patients in Shangke No.1 Formula group was better than that of the control group,and the measured value

关 键 词：中医 伤科一号方 膝关节 软组织损伤 中药塌渍 

分 类 号：R274[医药卫生—中医骨伤科学]