基于“亢害承制”理论从肝、肺论治帕金森病  

Treating Parkinson′s disease from the perspective of the liver and lung based on the theory of"restraining excessiveness to acquire harmony"

作　　者：王子雨 孙灵芝[2] WANG Ziyu;SUN Lingzhi(Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,China)

机构地区：[1]山东中医药大学,济南250014 [2]山东中医药大学附属医院

出　　处：《北京中医药大学学报》2024年第9期1282-1287,共6页Journal of Beijing University of Traditional Chinese Medicine

基　　金：山东省自然科学基金项目(No.ZR2021MH180);第五批全国中医临床优秀人才研修项目。

摘　　要：帕金森病的病机与脏腑、气血、阴阳失衡相关,受其复杂病机的影响,本病的部分症状呈现出特点相反和异常制约的现象。在气化层面,静止性震颤和肌强直分别呈现散和收两种相反的阳气运行状态;在神的层面,快速眼动睡眠行为障碍的产生是由于魂对于魄的异常制约。肝主升,肺主降;肝宜散,肺宜敛;肺制肝,金胜木,肝肺也具有相反和相互制约的特性。本文基于“亢害承制”理论探讨肝、肺在神、气化、脏腑功能3个层面与帕金森病的相关性,从3者的相互作用中得出帕金森病运动症状与非运动症状的联系,并阐述运动症状和非运动症状的产生及治疗方案。生理状态下,肝、肺通过维持“亢害承制”的动态平衡关系,以制而不克、和合共生;病理状态下,肝、肺的神、气化、脏腑功能均可出现异常,并相互为因。本文以肝、肺在神-气化-脏腑功能的“亢害承制”关系为切入点进行深入探讨,丰富帕金森病的病机,为本病的临床诊断及治疗提供新思路。The pathogenesis of Parkinson′s disease is related to the imbalance of viscera,qi,blood,and yin and yang.Some Parkinson′s symptoms show opposite characteristics and abnormal constraints because of the influence of its complex pathogenesis.At the qi transformation level,static tremor and muscular rigidity exhibit two opposite states of yang qi:dispersion and contraction.At the spirit level,the sleep disorder of rapid eye movement is caused by the abnormal constraint of the soul on the corporeal soul.The liver is in charge of ascending,whereas the lung is in charge of descending.The liver prefers to disperse,whereas the lung prefers to converge;the lung restrains the liver,and metal(representing the lungs)overcomes wood(representing the liver).Therefore,the liver and lung also possess opposing and mutually restraining characteristics.This study explored the correlation between the liver and lung of patients with Parkinson′s disease at the three levels of spirit,qi transformation,and viscera based on the theory of"restraining excessiveness to acquire harmony".It established the connection between motor and non-motor symptoms of Parkinson′s disease through the interaction of these three factors.The study elaborated on the generation of symptoms and treatment options for both motor and non-motor symptoms.Under physiological conditions,the liver and lung maintain a dynamic equilibrium of"restraining excessiveness from acquiring harmony"through restraint without suppression,promoting coexistence and harmony.However,under pathological conditions,the functions of the spirit,qi transformation,and viscera of the liver and lung may exhibit abnormalities,and they could mutually influence each other.This study investigated the"restraining excessiveness to achieve harmony"relationship between the liver and lung,focusing on spirit,qi transformation,and viscera levels.The aim of this study was to deepen the understanding of the pathogenesis of Parkinson′s disease and to offer novel insights into its clinical diagnosis a

关 键 词：帕金森病 亢害承制 肝 肺 运动症状 非运动症状 

分 类 号：R277.7[医药卫生—中医学]