慢性湿疹和荨麻疹患者过敏原特异性IgE与总IgE水平检测分析  

Detection and analysis of allergen specific IgE and total IgE levels in patients with chronic eczema and urticaria

作　　者：刘萍 卜彬彬 胡燕 王光应 Liu Ping;Bu Binbin;Hu Yan;Wang Guangying(Dermatology Department,Chuxiong People's Hospital,Chuxiong Yunnan,675000,China)

机构地区：[1]云南省楚雄州人民医院皮肤科,云南楚雄675000

出　　处：《中外女性健康研究》2024年第10期44-46,共3页Women＇s Health Research

摘　　要：目的:对血清过敏原特异性IgE与总IgE水平检测内容进行分析,探究慢性湿疹患者、荨麻疹患者应用效果。方法:选择本院2022年8月至2022年11月收治的皮肤病(慢性湿疹、慢性荨麻疹)患者210例,而后提供血清过敏原特异性IgE抗体检测结果、避免接触致敏原,对比最终效果,内容包括:血清过敏原反应结果、血清总IgE水平具体分布(<50IU/mL、50~90IU/mL、>90IU/mL)。结果:1)血清过敏原检测后,对特异性IgE水平展开评测;210例皮肤病(慢性湿疹、慢性荨麻疹)患者中,对血清过敏原检测结果展开分析,阳性率为77.62%(163/210),其中38例患者对1种过敏原呈阳性,125例患者对2种及以上过敏原呈阳性,所占百分比为23.31%、76.69%;其过敏原具体类型有:花生、腰果、芒果、桃子,小麦,鸡蛋,牛肉、牛奶、虾,鳕鱼,狗上皮,猫上皮,屋尘螨粉尘螨,烟曲霉,交链孢霉,蟑螂,柳树,艾蒿,普通豚草;2)关于血清总IgE水平,<50IU/mL的慢性湿疹、慢性荨麻疹患者有160例,具体分布为35例(21.88%)、125例(78.13%);血清总IgE水平处于50~90IU/mL患者有38例,在慢性湿疹患者、慢性荨麻疹患者中,具体分布为12例(31.58%)、26例(68.42%),12例患者血清总IgE水平>90IU/mL,在慢性湿疹患者、慢性荨麻疹患者中,具体分布为4例(33.33%)、8例(66.67%)。结论:临床上血清过敏原特异性IgE抗体检测有重要意义,可提高慢性湿疹、慢性荨麻疹检出率,为医生治疗疾病提供重要参考。Objective:To analyze the content of serum allergen specific IgE antibody and total IgE level detection to explore the application effect in chronic eczema patients and urticaria patients.Methods:A total of 210 patients with skin diseases(chronic eczema and chronic urticaria)admitted to the Hospital from August 2022 to November 2022 were selected as reference,then serum allergen specific IgE antibody detection was provided to compare the final effect,including:Results of serum allergen reaction,specific distribution of serum total IgE level(<50IU/mL,50~90 IU/mL,>90 IU/mL).Results:1)After the detection of serum allergens,the specific IgE level was evaluated.In the healthy population,with the specific value<20IU/mL;Among 210 patients with skin diseases(chronic eczema and chronic urticaria),the positive rate of serum allergens was 77.62%(163/210).Among them,38 patients were positive for one allergen and 125 patients were positive for two or more allergens,accounting for 23.31%and 76.69%respectively;The specific types of allergens are:peanut,soybean,egg yolk,protein,mutton,beef,milk,sea crab,sea fish,sea shrimp,spring pollen,artemisia plants,ragweed pollen,multivalent mold,house dust,dust mites;2)With regard to the total serum IgE level,160 patients with chronic eczema and chronic urticaria were less than 50 IU/mL,and the specific distribution was 35 cases(21.88%)and 125 cases(78.13%);There were 38 patients with total serum IgE levels of 50-90 IU/mL,12 patients(31.58%)and 26 patients(68.42%)with chronic eczema and chronic urticaria,and 12 patients with total serum IgE levels>90 IU/mL,4 patients(33.33%)and 8 patients(66.67%)with chronic eczema and chronic urticaria.Conclusion:In clinical practice,the detection of serum allergen specific IgE antibody is of great significance,which can improve the detection rate of chronic eczema and chronic urticaria,provide important reference for doctors to treat diseases,and has significant promotion value.

关 键 词：血清过敏原 特异性IGE 总IgE水平 慢性湿疹患者 荨麻疹患者 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]