柴朴汤治疗痰气痹阻型胸闷变异性哮喘临床观察  

Efficacy observation of Chaipu decoction on chest tightness variant asthma with syndrome of obstruction of phlegm and qi

作　　者：丁湘 郑远方 DING Xiang;ZHENG Yuan-fang(Changde Hospital Affiliated to Hunan University of Traditional Chinese Medicine,Changde 415000,China)

机构地区：[1]湖南中医药大学附属常德医院,常德415000

出　　处：《山西中医》2024年第10期11-13,共3页Shanxi Journal of Traditional Chinese Medicine

摘　　要：目的:观察柴朴汤治疗痰气痹阻型胸闷变异性哮喘的临床疗效。方法:将符合纳入标准的64例痰气痹阻型胸闷变异性哮喘患者,随机分为两组各32例。对照组予口服孟鲁司特钠治疗,治疗组在对照组基础上加用柴朴汤治疗,比较两组临床疗效。结果:治疗组总有效率93.75%,高于对照组的78.13%,两组比较差异有统计学意义(P﹤0.05);治疗后,治疗组外周血嗜酸性粒细胞(EOS)、血清总IgE、呼出气一氧化氮(FeNO)水平均低于对照组(P﹤0.05);治疗组第1秒用力呼气容积(FEV1)、呼吸流量峰值(PEF)水平均高于对照组(P﹤0.05)。结论:柴朴汤治疗痰气痹阻型胸闷变异性哮喘疗效较好,可减轻炎性反应,改善肺功能。Objective:To observe the clinical efficacy of Chaipu decoction on chest tightness variant asthma with syndrome of obstruction of phlegm and qi.Methods:64 cases of eligible patients with chest tightness variant asthma with syndrome of obstruction of phlegm and qi were randomly divided into two groups,32 cases in each group.The control group was treated with oral montelukast,while the treatment group was treated plus with Chaipu decoction on the basis of control group.The clinical efficacy was compared between two groups.Results:The total effective rate of treatment group was 93.75%,which was higher than 78.13%of control group,and the comparative difference between two groups was statistically significant(P﹤0.05).After treatment,the levels of eosinophils(EOS)in peripheral blood,total IgE in serum and fractional exhaled nitric oxide(FeNO)of treatment group were lower than those of control group(P﹤0.05);the levels of forced expiratory volume in one second(FEV1)and peak expiratory flow rate(PEF)of treatment group were higher than those of control group(P﹤0.05).Conclusion:The clinical efficacy of Chaipu decoction on chest tightness variant asthma with syndrome of obstruction of phlegm and qi is better,which can reduce inflammatory reaction and improve lung function.

关 键 词：胸闷变异性哮喘 痰气痹阻 柴朴汤 中医药疗法 

分 类 号：R256.12[医药卫生—中医内科学]