类风湿关节炎中医证候分布规律及不同证型血沉、C反应蛋白的差异性分析  

Analysis of distribution rule of TCM syndromes of rheumatoid arthritis and differences of erythrocyte sedimentation rate and C-reactive protein of different syndromes types

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作  者:范静 张金山 徐宇 张莉萍 FAN Jing;ZHANG Jin-shan;Xu Yu(Taihe Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Traditional Chinese Medicine,Taihe 236600,China)

机构地区:[1]安徽中医药大学附属太和中医院,太和236600

出  处:《山西中医》2024年第10期49-51,共3页Shanxi Journal of Traditional Chinese Medicine

基  金:安徽省阜阳市重点临床科研项目(编号:FYZDYF2023LCYX031);安徽中医药大学临床科研项目(编号:2023LCTH13)。

摘  要:目的:分析类风湿关节炎中医征候分布规律及不同证型血沉、C反应蛋白的差异性。方法:纳入500例类风湿关节炎患者的横断面资料,对不同中医证型之间性别、年龄、病程、共患心血管疾病及血沉、C反应蛋白进行统计学分析。结果:①与≤60岁组比较,﹥60岁组肝肾亏虚证、气阴两虚证较多,而风湿痹阻证、气血两虚证较少(P﹤0.05);②与男性组比较,女性组风湿痹阻证、寒湿痹阻证、气血两虚证较多,而湿热痹阻证、瘀血阻络证较少(P﹤0.05);③与病程﹥15年组比较,病程≤5年、病程6~15年组痰瘀痹阻证较少,风湿痹阻证较多(P﹤0.05);与病程≤5年组比较,病程6~15年组风湿痹阻证较少(P﹤0.05);④与不共患心血管疾病组比较,共患心血管疾病组痰瘀痹阻证、肝肾亏虚证较多,风湿痹阻证较少(P﹤0.05);⑤与痰瘀痹阻证比较,风湿痹阻证和气血两虚证血沉中位数较低(P﹤0.05);与气血两虚证比较,湿热痹阻证、痰瘀痹阻证、气阴两虚证C反应蛋白中位数较高(P﹤0.05);与风湿痹阻证相比,湿热痹阻证、痰瘀痹阻证、气阴两虚证C反应蛋白中位数较高(P﹤0.05)。结论:不同证型类风湿关节炎在性别、年龄、病程、共患心血管疾病及血沉、C反应蛋白方面存在着显著性差异。Objective:To analyze the distribution rule of TCM syndromes of rheumatoid arthritis and differences of erythrocyte sedimentation rate(ESR)and C-reactive protein of different syndromes.Methods:The cross-sectional data of 500 patients with rheumatoid arthritis were included.The correlativity between different TCM syndrome types of rheumatoid arthritis and age,gender,course of disease,comorbidity of cardiovascular disease,erythrocyte sedimentation rate and C-reactive protein were analyzed statistically.Results:1.Compared with the group of≤60 years old,syndrome of deficiency of liver and kidney and syndrome of deficiency of both qi and yin were more in the group of﹥60 years old,while syndrome of wind-dampness obstruction and syndrome of deficiency of both qi and blood were less(P﹤0.05).2.Compared with male group,syndrome of wind-dampness obstruction,syndrome of cold-dampness obstruction and syndrome of deficiency of both qi and blood were more in female group,while syndrome of damp-heat obstruction and syndrome of blood-stasis obstruction in collaterals were less(P﹤0.05).3.Compared with the group with disease course﹥15 years,for the disease course≤5 years and 6-15 years,syndrome of phlegm-blood stasis obstruction was less,while syndrome of wind-dampness obstruction was more(P﹤0.05).Compared with the group with disease course≤5 years,for the disease course for 6-15 years,syndrome of wind-dampness obstruction was less(P﹤0.05).4.Compared with the group with non-comorbidity of cardiovascular disease,in the group with comorbidity of cardiovascular disease,syndrome of phlegm-blood stasis obstruction and syndrome of deficiency of liver and kidney were more,while syndrome of wind-dampness obstruction was less(P﹤0.05);5.Compared with syndrome of phlegm-blood stasis obstruction,the median of erythrocyte sedimentation rate of syndrome of wind-dampness obstruction and syndrome of deficiency of both qi and blood was lower(P﹤0.05).Compared with syndrome of deficiency of both qi and blood,the median of C-react

关 键 词:类风湿关节炎 中医证型 差异性 

分 类 号:R593.22[医药卫生—内科学]

 

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