血栓弹力图与常规凝血相关指标诊断肿瘤术后产生深静脉血栓的价值研究  

Study on the Value of Thromboelastography and Conventional Coagulation Related Indexes in Diagnosing Deep Vein Thrombosis after Tumor Operation

作　　者：杨志刚 任颖[1] 张洁[1] YANG Zhigang;REN Ying;ZHANG Jie(Department of Blood Transfusion,First Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi,China)

机构地区：[1]山西医科大学第一医院输血科,山西太原030001

出　　处：《系统医学》2024年第16期1-4,共4页Systems Medicine

基　　金：山西医科大学第一医院院基金项目(YY2205)。

摘　　要：目的 探究肿瘤术后产生深静脉血栓(deep venous thrombosis,DVT)诊断中采用血栓弹力图与常规凝血指标诊断价值。方法 目的选取山西医科大学第一医院2022年2月—2023年9月收治的120例行肿瘤手术的患者,根据30 d内是否发生DVT划分为发生组与未发生组,各60例。分别对上述两组进行血栓弹力图与常规凝血指标检测,对比两组指标变化以及检测效能。结果 发生组患者R值、K值低于未发生组,α角、MA值高于未发生组,差异有统计学意义(P均<0.05)。发生组患者纤维蛋白原(4.21±0.94)g/L高于未发生组的(3.23±0.68)g/L,差异有统计学意义(t=6.555,P<0.05)。两组活化凝血活酶时间、凝血酶原时间和凝血酶时间对比,差异无统计学意义(P均>0.05)。血栓弹力图与常规凝血相关指标在肿瘤术后深静脉血栓诊断中应用结果对比分析发现,血栓弹力图指标中的R值、K值、α角和纤维蛋白原指标在肿瘤术后深静脉血栓诊断中具有较高的诊断效能,联合检测诊断价值优于单一指标,差异有统计学意义(P均<0.05)。结论 R值、K值、α角和FIB指标在肿瘤术后深静脉血栓诊断中具有较高的校验效能,联合诊断更为显著,应当重视上述指标联合检测。Objective To investigate the value of using thromboelastography and conventional coagulation indexes in the diagnosis of deep venous thrombosis(DVT) after tumor surgery.Methods 120 tumor patients admitted to the First Hospital of Shanxi Medical University from February 2022 to September 2023 were objectively selected and divided into a developing group and a non-developing group with 60 cases according to whether DVT occurred within 30 days.Thromboelastography and conventional coagulation indexes were detected respectively in the above two groups,and the changes and detection efficiency of the two groups were compared.Results The R value and K value in the occurrence group were lower than those in the non-occurrence group,and the α Angle and MA value in the occurrence group were higher than those in the non-occurrence group,the differences were statistically significant(all P<0.05).The Fibrinogen(FIB) level of patients in the developing group was(4.21±0.94) g/L,higher than(3.23±0.68) g/L in the non-developing group,the difference was statistically significant(t=6.555,P<0.05) There were no statistically significant differences in activated partial thromboplatin time,prothrombin time and thrombin time between the two groups(all P>0.05).A comparative analysis of the application results of thromboelastography and conventional clotting related indicators in the diagnosis of deep vein thrombosis after tumor surgery showed that the R value,K value,αAngle and FIB indexes in the thromboelastography indicators had higher efficacy in the diagnosis of deep vein thrombosis after tumor surgery,and the combined diagnostic value was better than single index,the differences were statistically significant(all P<0.05).Conclusion R value,K value,α Angle and FIB index have higher calibration efficiency in the diagnosis of deep vein thrombosis after tumor surgery,and the combined diagnosis is more significant.

关 键 词：肿瘤 深静脉血栓 血栓弹力图 凝血功能 R值 反应时间 α角 

分 类 号：R4[医药卫生—临床医学]