容积弧形调强放疗与静态调强放疗在宫颈癌根治性放疗中的剂量学分析  

Dosimetric Analysis of Volumetric Modulated Arc Therapy and Static Intensity Modulated Radiation Therapy in Radical Radiotherapy for Cervical Cancer

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作  者:丁文秀[1] 李树要 周绍兵[1] DING Wenxiu;LI Shuyao;ZHOU Shaobing(Radiotherapy Department,Taixing People's Hospital,Taizhou 225400,Jiangsu,China)

机构地区:[1]泰兴市人民医院放疗科,江苏泰州225400

出  处:《系统医学》2024年第16期155-158,共4页Systems Medicine

摘  要:目的 研究观察容积弧形调强放疗与静态调强放疗在宫颈癌根治性放疗中的剂量学。方法 目的选取泰兴市人民医院2018年1月—2023年12月收治的60例宫颈癌患者,根据治疗方法不同分组,每组30例,观察组进行容积弧形调强放疗,对照组进行静态调强放疗。比较二者靶区和危及器官的剂量分布、总机器跳数和有效治疗时间。结果 观察组患者临床靶体积-计划靶体积及临床靶体积-计划靶体积的D2%、D95%、CI的受照剂量均高于对照组,而HI、D98%指标低于对照组患者;其危及器官(小肠、脊髓、直肠、股骨头)Dmean、V40及D2%的受照剂量均少于对照组患者,差异有统计学意义(P均<0.05)。观察组患者的有效治疗时间(82.35±6.34)d及总机器跳数518.34±22.33均少于对照组患者的(342.72±10.62)d及635.52±42.52,差异有统计学意义(t=115.301、13.363,P均<0.05)。结论 两种放疗方式均可达到剂量学要求,但相较于静态调强放疗,容积弧形调强放疗法计划靶区均匀性、适形度更佳,危及器官的剂量更少。Objective To investigate the dosimetry of volumetric arc modulated radiotherapy and static intensitymodulated radiotherapy in radical radiotherapy for cervical cancer.Methods Sixty cervical cancer patients admitted to Taixing City People's Hospital from January 2018 to December 2023 were objectively selected,and they were divided into two groups by different treatment methods,with thirty cases in each group,the observation group underwent volumetric arc modulated radiotherapy and the control group underwent static intensity-modulated radiotherapy).The dose distribution,total number of machine hops and effective treatment time of the target area and the endangered organs were compared.Results The dose of D2 %,D95 % and CI of clinical target volume-planned target volume and clinical target volume-planned target volume in the observation group were higher than those in the control group,while the HI and D98 % indexes were lower than those in the control group.The doses of Dmean,V40 and D2 % of the organs at risk(small intestine,spinal cord,rectum and femoral head) were less than those of the control group,and the difference was statistically significant(all P<0.05).The effective treatment time(82.35±6.34) d and total machine jumps 518.34±22.33 of the observation group patients were lower than those of the control group patients(342.72±10.62) d and 635.52±42.52,the differences were statistically significant(t=115.301,13.363,both P<0.05).Conclusion Both radiotherapy modalities can meet the dosimetry requirements,but compared with static intensity-modulated radiotherapy,the target area uniformity and conformity of the volumetric arc intensity-modulated radiotherapy plan are better,and the dose that endangers organs is less.

关 键 词:容积弧形调强放疗 静态调强放疗 宫颈癌 剂量分布 

分 类 号:R614[医药卫生—麻醉学]

 

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