Effect of changing the proportion of C16:0 and cis-9 C18:1 in fat supplements on rumen fermentation,glucose and lipid metabolism,antioxidation capacity,and visceral fatty acid profile in finishing Angus bulls  

作　　者：Haixin Bai Lubo Wang Modinat Tolani Lambo Yang Li Yonggen Zhang 

机构地区：[1]College of Animal Science and Technology,Northeast Agricultural University,Harbin 150030,China

出　　处：《Animal Nutrition》2024年第3期39-48,共10页动物营养（英文版）

基　　金：supported by the earmarked fund for CARS36,the Natural Science Foundation of Heilongjiang Province,China (YQ2023C011);the"Academic Backbone"Project of Northeast Agricultural University.China (22XG35).

摘　　要：This study evaluated the effects of different proportions of palmitic(C16:0)and oleic(cis-9 C18:1)acids in fat supplements on rumen fermentation,glucose(GLU)and lipid metabolism,antioxidant function,and visceral fat fatty acid(FA)composition in Angus bulls.The design of the experiment was a randomized block design with 3 treatments of 10 animals each.A total of 30 finishing Angus bulls(21±0.5 months)with an initial body weight of 626±69 kg were blocked by weight into 10 blocks,with 3 bulls per block.The bulls in each block were randomly assigned to one of three experimental diets:(1)control diet without additional fat(CON),(2)CON+2.5%palmitic calcium salt(PA;90%C16:0),(3)CON+2.5%mixed FA calcium salts(MA;60%C16:0+30%cis-9 C18:1).Both fat supplements increased C18:0 and cis-9 C18:1 in visceral fat(P<0.05)and up-regulated the expression of liver FA transport protein 5(FATP5;P<0.001).PA increased the insulin concentration(P<0.001)and aspartate aminotransferase activity(AST;P=0.030)in bull's blood while reducing the GLU concentration(P=0.009).PA increased the content of triglycerides(TG;P=0.014)in the liver,the content of the C16:0 in visceral fat(P=0.004),and weight gain(P=0.032),and up-regulated the expression of liver diacylglycerol acyltransferase 2(DGAT2;P<0.001)and stearoyl-CoA desaturase 1(SCD1;P<0.05).MA increased plasma superoxide dismutase activity(SOD;P=0.011),reduced the concentration of acetate and total volatile FA(VFA)in rumen fluid(P<0.05),and tended to increase plasma non-esterified FA(NEFA;P=0.069)concentrations.Generally,high C16:0 fat supplementation increased weight gain in Angus bulls and triggered the risk of fatty liver,insulin resistance,and reduced antioxidant function.These adverse effects were alleviated by partially replacing C16:0 with cis-9 C18:1.

关 键 词：Palmitic acid Oleic acid Lipid metabolism LIPOTOXICITY Finishing bull 

分 类 号：S823.5[农业科学—畜牧学]