理气消癥止痛方联合抗生素治疗慢性盆腔炎临床研究  

Clinical Study on Liqi Xiaozheng Zhitong Prescription Combined with Antibiotics for Chronic Pelvic Inflammatory Disease

作　　者：马秀玲 彭振 周淑蓓 MA Xiuling;PENG Zhen;ZHOU Shubei(Obstetrics and Gynecology Department,Zhoukou Hospital of Traditional Chinese Medicine,Zhoukou Henan 466000,China;Interventional Department,Zhoukou Xiehe Orthopedic Hospital,Zhoukou Henan 466000,China)

机构地区：[1]周口市中医院妇产科,河南周口466000 [2]周口市协和骨科医院介入科,河南周口466000

出　　处：《新中医》2024年第19期111-115,共5页New Chinese Medicine

摘　　要：目的:观察理气消癥止痛方联合抗生素治疗慢性盆腔炎的临床疗效。方法:回顾性分析106例慢性盆腔炎患者的临床资料,依照治疗方式不同分为常规西医组和中西医结合组各53例。常规西医组给予抗生素治疗,中西医结合组在常规西医组基础上加用理气消癥止痛方治疗。比较2组临床疗效,以及治疗前后中医证候评分、炎症因子水平及血流动力学指标。结果:中西医结合组总有效率92.45%,高于常规西医组77.36%(P<0.05)。治疗后,2组少腹刺痛、腰骶胀痛、带下异常等中医证候评分均降低(P<0.05),且中西医结合组各项评分均低于常规西医组(P<0.05)。治疗后,2组血清单核细胞趋化蛋白-1(MCP-1)、细胞间黏附分子-1(ICAM-1)、转化生长因子-β(TGF-β)水平均降低(P<0.05),且中西医结合组低于常规西医组(P<0.05)。治疗后,2组盆腔最大血流速度(Vmax)、收缩期峰值血流速度(PSV)水平均升高(P<0.05),且中西医结合组高于常规西医组(P<0.05);2组盆腔搏动指数(PI)、阻力指数(RI)水平均降低(P<0.05),且中西医结合组低于常规西医组(P<0.05)。结论:理气消癥止痛方联合抗生素可改善慢性盆腔炎患者炎症状态,调控血流动力学水平,改善中医证候,临床疗效良好。Objective:To observe the clinical effect of Liqi Xiaozheng Zhitong Prescription combined with antibiotics in the treatment of patients with chronic pelvic inflammatory disease.Methods:The clinical data of 106 patients with chronic pelvic inflammatory disease were given retrospective analysis,and divided into the routine western medicine group and the integrated Chinese and western medicine group according to different treatment methods,with 53 cases in each group.The routine western medicine group was treated with antibiotics,and the integrated Chinese and western medicine group was additionally treated with Liqi Xiaozheng Zhitong Prescription on the basis of the routine western medicine group.Compared the clinical efficacy of the two groups,and compared the traditional Chinese medicine(TCM)syndrome scores,inflammatory factor levels,and hemodynamic indicators before and after treatment between the two groups.Results:The total clinical effective rate was 92.45%in the integrated Chinese and western medicine group,which was higher than that of 77.36%in the routine western medicine group(P<0.05).After treatment,the scores of TCM syndromes such as low abdominal stabbing pain,lumbosacral distension and pain,and abnormal vaginal discharge were declined in both groups(P<0.05),and the scores in the integrated Chinese and western medicine group were lower than those in the routine western medicine group(P<0.05).After treatment,the levels of serum monocyte chemotactic protein-1(MCP-1),intercellular adhesion molecule-1(ICAM-1),and transforming growth factor-β(TGF-β)were decreased in both groups(P<0.05),and the scores in the integrated Chinese and western medicine group were lower than those in the routine western medicine group(P<0.05).After treatment,the maximum pelvic blood flow velocity(Vmax)and peak systolic blood flow velocity(PSV)levels in both groups were raised(P<0.05),and the levels in the integrated Chinese and western medicine group were higher than those in the routine western medicine group(P<0.05);the levels

关 键 词：慢性盆腔炎 理气消癥止痛方 抗生素 炎症因子 血流动力学 

分 类 号：R271.9[医药卫生—中西医结合]