穴位贴敷联合额三针治疗失眠临床研究  

Clinical Study on Point Application Combined with Frontal-Three-Needle for Insomnia

作　　者：丁成竟 蔡剑飞[1] 刘鸿[1] DING Chengjing;CAI Jianfei;LIU Hong(Department of Acupuncture and Moxibustion,Lishui Hospital of Traditional Chinese Medicine,Lishui Zhejiang 323000,China)

机构地区：[1]丽水市中医院针灸科,浙江丽水323000

出　　处：《新中医》2024年第19期168-172,共5页New Chinese Medicine

摘　　要：目的:观察穴位贴敷联合额三针治疗失眠的疗效。方法:选取116例失眠患者,按随机数字表法分为对照组及观察组各58例。对照组给予穴位贴敷治疗,观察组在穴位贴敷基础上给予额三针治疗。比较2组临床疗效,比较2组治疗前后相关神经递质[褪黑素、5-羟色胺(5-HT)、食欲素A、多巴胺(DA)]、睡眠日记、匹兹堡睡眠质量指数(PSQI)评分的变化。结果:治疗后,2组褪黑素、5-HT指标值均较治疗前上升(P<0.05),食欲素A、DA水平均较治疗前下降(P<0.05);观察组褪黑素、5-HT水平高于对照组(P<0.05),食欲素A、DA水平均低于对照组(P<0.05)。治疗后,2组睡眠总时间(TST)、睡眠效率(SE)指标值均较治疗前上升(P<0.05),睡眠潜伏期(SOL)指标值均较治疗前下降(P<0.05);观察组TST、SE水平均高于对照组(P<0.05),SOL水平低于对照组(P<0.05)。治疗后,2组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、安眠药物、日间功能障碍及PSQI总分均较治疗前下降(P<0.05),观察组上述7项PSQI评分及总分均低于对照组(P<0.05)。观察组临床疗效总有效率为93.10%,对照组为79.31%,2组比较,差异有统计学意义(P<0.05)。结论:穴位贴敷联合额三针治疗失眠可调节相关神经递质的表达,减轻睡眠障碍症状,改善睡眠质量。Objective:To observe the curative effect of point application combined with frontal-three-needle on insomnia.Methods:A total of 116 patients with insomnia were selected and divided into the control group and the observation group according to the random number table method,with 58 cases in each group.The control group received point application,and the observation group received frontal-three-needle treatment on the basis of point application.Compared the clinical effects of the two groups and compared the changes in related neurotransmitters[melatonin,5-hydroxytryptamine(5-HT),orexin A,dopamine(DA)],sleep diary,and Pittsburgh Sleep Quality Index(PSQI)scores before and after treatment in the two groups.Results:After treatment,the levels of melatonin and 5-HT in both groups were increased when compared with those before treatment(P<0.05),and the levels of orexin A and DA were decreased when compared with those before treatment(P<0.05);the levels of melatonin and 5-HT in the observation group were higher than those in the control group(P<0.05),and the levels of orexin A and DA were both lower(P<0.05).After treatment,both totalsleeptime(TST)and sleep efficiency(SE)index values were increased when compared with those before treatment(P<0.05),and sleep onset latency(SOL)index values were decreased when compared with those before treatment(P<0.05);the TST and SE index values in the observation group were higher than those in the control group(P<0.05),and the SOL index value was lower than that in the control group(P<0.05).After treatment,the sleep quality,falling asleep time,sleep duration,sleep efficiency,sleep disorders,sleeping pills,daytime dysfunction,and PSQI total scores in both groups were decreased when compared with those before treatment(P<0.05).The above seven scores and the total score in the observation group were lower than those in the control group(P<0.05).The total effective rate of clinical efficacy was 93.10%in the observation group,and 79.31%in the control group,the difference being significant(P<0

关 键 词：失眠 穴位贴敷 额三针 针刺 神经递质 睡眠质量 

分 类 号：R256.23[医药卫生—中医内科学]