ELISA单试剂反应性献血者归队情况调查研究  

Investigation on the return of blood donors with ELISA single reagent reaction

作　　者：胥灏 范恩勇 孙海英 郇亮 XU Hao;FAN Enyong;SUN Haiying;HUAN Liang(Department of Clinical Laboratory,Yangzhou Blood Center,Yangzhou 225000,Jiangsu,China)

机构地区：[1]扬州市中心血站检验科,江苏扬州225000

出　　处：《中国现代医生》2024年第28期10-13,共4页China Modern Doctor

基　　金：江苏省卫生健康委科研项目(Z2022060)。

摘　　要：目的探讨酶联免疫吸附试验(enzyme linked immunosorbent assay,ELISA)单试剂反应性献血人群归队情况及影响因素。方法选取扬州市中心血站2018年1月至2023年12月申请归队的献血者291例为研究对象,根据是否归队成功将其分为归队组(n=186)与屏蔽组(n=105),分析献血者归队不合格的原因。采用多因素Logistic回归分析单试剂反应性献血者归队的影响因素。结果献血者乙肝两对半不合格人数最多,占69.52%,其次为梅毒螺旋体明胶颗粒凝集试验,占7.62%。归队组献血者多次献血、献血间隔时间短、献全血、接种乙肝疫苗的占比显著高于屏蔽组(P<0.05)。多因素Logistic回归分析结果显示,献血次数、间隔时间、献血类型、接种乙肝疫苗是单试剂反应性献血者归队的独立影响因素(P<0.05)。结论扬州地区献血间隔时间短、献血次数多、献血类型为全血及接种乙肝疫苗的单试剂反应性献血者成功归队概率较高。Objective To investigate the return status of blood donors with single reagent reaction to enzyme linked immunosorbent assay(ELISA)and its influencing factors.Methods A total of 291 blood donors who applied to return from January 2018 to December 2023 in Yangzhou Blood Center were selected as research objects,and were divided into returning group(n=186)and shielding group(n=105)according to whether they were successfully returned.The causes of unqualified blood donors were analyzed,and the influencing factors of blood donors with single reagent reaction were analyzed by multivariate Logistic regression.Results The number of hepatitis B two-for-half unqualified blood donors was the largest,accounting for 69.52%,followed by treponema pallidum particle agglutination assay,accounting for 7.62%.The proportion of repeated blood donation,short interval of blood donation,whole blood donation and vaccination of hepatitis B vaccine in returning group were significantly higher than those in shielding group(P<0.05).Multivariate Logistic regression analysis showed that the number of blood donation,interval time,type of blood donation and vaccination of hepatitis B vaccine were independent factors influencing the return of single reagent reactive blood donors(P<0.05).Conclusion In Yangzhou area,the probability of successful return is higher in the single reagent reactive blood donors with short interval of blood donation,more blood donation times,whole blood donation type and vaccination of hepatitis B vaccine.

关 键 词：无偿献血者 单试剂反应性 归队 影响因素 

分 类 号：R446.6[医药卫生—诊断学]