基于数据挖掘治疗肺癌的用药规律  

Drug use patterns in the treatment of lung cancer based on data mining

作　　者：季兴祖 郑勇飞[1] 周敏华 叶益平 JI Xingzu;ZHENG Yongfei;ZHOU Minhua;YE Yiping(Department of Oncology of Traditional Chinese Medicine,Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University,Lishui 323000,Zhejiang,China)

机构地区：[1]浙江中医药大学附属丽水中医院中医肿瘤科,浙江丽水323000

出　　处：《中国现代医生》2024年第28期71-75,共5页China Modern Doctor

基　　金：浙江省丽水市科技计划项目(2022SJZC040)。

摘　　要：目的基于中医传承辅助平台,深入分析治疗肺癌的用药规律。方法收集2022年1月至2023年9月于浙江中医药大学附属丽水中医院门诊治疗肺癌患者的有效处方200首,录入中医传承辅助平台,对药物进行关联规则和聚类分析。结果共纳入有效处方200首,涉及中药146味。所用药物的药性以寒、温、平为主,药味以甘、苦、辛为主,主要归肺、脾、胃、心经。使用频次较高的中药依次为羊乳、甘草、丹参、姜半夏、猫人参、浙贝母等,得到核心药物组合27组,新方5个。结论肺癌临证辨治紧扣“阴虚瘀毒”核心病机,同时顾护后天脾胃、心身同调,体现扶正抗癌及中医整体观的中医肿瘤学术思想。Objective To explore drug use patterns in treatment of lung cancer based on traditional Chinese medicine inheritance assistance platform.Methods A total of 200 effective prescriptions for the treatment of lung cancer patients in the outpatient department of Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University from January 2022 to September 2023 were collected and input into the traditional Chinese medicine inheritance assistance platform to conduct association rules and cluster analysis of drugs.Results A total of 200 effective prescriptions were included,involving 146 traditional Chinese medicines.The medicinal properties were mainly cold,warm and flat,and the medicinal flavours were mainly sweet,bitter and pungent,which mainly belong to lung,spleen,stomach and heart meridian.The most frequently used Chinese medicines were Radix Codonopsis Lanceolatae,Radix et Rhizoma Glycyrrhizae,Radix et Rhizoma Salviae Miltiorrhizae,Rhizoma Pinelliae,Actinidia valvata Dunn,Fritillariae Thunbergii Bulbus,etc.27 groups of core drug combinations were obtained,and 5 new prescriptions were obtained.Conclusion Clinical diagnosis and treatment of lung cancer is closely related to the core pathogenesis of Yin deficiency and stasis toxicity,and at the same time,it takes care of the acquired spleen and stomach,mind-body harmony,reflecting the academic thought of traditional Chinese medicine tumor,which reinforce healthy qi to anti-cancer and the holistic view of traditional Chinese medicine.

关 键 词：数据挖掘 中医传承辅助平台 肺癌 用药规律 

分 类 号：R273[医药卫生—中西医结合]