叶酸缺乏对骨骼肌损伤的研究进展  

Research progress of folic acid deficiency on skeletal muscle

作　　者：余爱勇 张瑜[1] YU Aiyong;ZHANG Yu(Department of Neurology,Song Jiang Hospital Affiliated to Shanghai Jiao Tong University of Medicine,Shanghai,201699,China)

机构地区：[1]上海交通大学医学院附属松江医院神经内科,上海201699

出　　处：《当代医学》2024年第16期191-194,共4页Contemporary Medicine

基　　金：松江区科学技术攻关项目(15SJGG30)。

摘　　要：叶酸是人体一种必需的水溶性维生素,通过介导一碳单元的转移,促进核苷酸的生物合成。叶酸缺乏症与多种因素有关,叶酸缺乏还会增加肌肉无力、行走困难及跌倒的发生风险。然而,叶酸缺乏到底是如何影响骨骼肌的,其分子机制是什么?本文旨在对叶酸缺乏对骨骼肌细胞的影响作一综述。Folic acid is an essential water-soluble vitamin that promotes nucleotide biosynthesis by mediating the transfer of one carbon unit.Folate deficiency is associated with a variety of factors,and it also increases the risk of muscle weakness,difficulty walking,and falls.However,how exactly does folate deficiency affect skeletal muscle,and what are the molecular mechanisms?This article aims to review the effects of folate deficiency on skeletal muscle cells.

关 键 词：叶酸 同型半胱氨酸 骨骼肌 

分 类 号：R685.4[医药卫生—骨科学]