食品乳化剂与肠道健康  

Dietary emulsifiers and intestinal health

作　　者：刘绍庭 张薇薇 冉茜 王建 LIU Shaoting;ZHANG Weiwei;RAN Qian;WANG Jian(Department of Nutrition,the Second Affiliated Hospital of Amy Medical University,Chongqing 400037,China;Department of Blood Transfusion,the Second Affiliated Hospital of Amy Medical University,Chongqing 400037,China)

机构地区：[1]陆军军医大学第二附属医院营养科,重庆400037 [2]陆军军医大学第二附属医院输血科,重庆400037

出　　处：《山东大学学报（医学版）》2024年第8期18-26,共9页Journal of Shandong University:Health Sciences

基　　金：重庆市杰出青年基金(cstc2021jcyj-jqX0004);陆军军医大学第二附属医院青博重点项目(2022YQB010)。

摘　　要：随着食品工业的发展,乳化剂在食品加工中的应用日益广泛,但其对肠道健康的影响也逐渐成为公众关注的焦点。乳化剂能够通过改变肠道菌群的结构和丰度,加剧肠道炎症反应,同时其能破坏肠道屏障、降低其完整性、增加肠道疾病风险。此外,乳化剂摄入与代谢综合征的关联亦不容忽视,会促进肥胖、高血糖等代谢异常。最令人担忧的是,孕期或哺乳期摄入乳化剂还可能对下一代的健康产生不良影响。本综述就目前国内外对乳化剂各种潜在危害的研究进行总结分析,探讨其对人体尤其是肠道系统健康的影响。With the advancement of the food industry,dietary emulsifiers have gained widespread usage in food processing.However,their impact on intestinal health has increasingly become a matter of public concern.Emulsifiers can aggravate inflammatory responses within the intestines by altering the structure and abundance of intestinal flora.Simultaneously,they can compromise the integrity of the intestinal barrier,thereby elevating the risk of intestinal diseases.Furthermore,it is crucial not to overlook the association between emulsifier consumption and metabolic syndrome as it may contribute to metabolic abnormalities such as obesity and hyperglycemia.Most alarmingly,consuming emulsifiers during pregnancy or breastfeeding may also exert adverse effects on future generationshealth.This review aims to summarize and analyze current domestic and international research regarding various potential hazards associated with emulsifiers,and focusing particularly on their impact on human health,specifically the gastrointestinal system.

关 键 词：乳化剂 肠道炎症 肠屏障 肠道菌群 肠道内稳态 

分 类 号：R459.3[医药卫生—治疗学] R574[医药卫生—临床医学]