Waterproof Perovskite Quantum Dots for In-vivo Photoluminescence Bioimaging  

作　　者：JIAO Ziyue WANG Xinli GAO Jie HUANG Xiao WANG Yi 

机构地区：[1]Key Laboratory of Advanced Light Conversion Materials and Biophotonics,School of Chemistry and Life Resources,Renmin University of China,Beijing,100872,P.R.China

出　　处：《Chemical Research in Chinese Universities》2024年第5期901-906,共6页高等学校化学研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.22373114,22103096,and 22273119);Beijing Natural Science Foundation,China(No.2232008)and the Research Funds of Renmin University of China(No.22XNKJ08).

摘　　要：Perovskite quantum dots(PQDs)have demonstrated great promise in bioimaging applications owing to their outstanding photophysical properties.Nonetheless,their practicality is seriously limited by the instability of PQDs against moisture.Here we develop a post-synthetic ligand exchange strategy to construct silica-coated PQD(PQD@SiO_(2))nanocrystals,which results in the simultaneous improvement of photoluminescence efficiency and moisture stability.More importantly,compared to the classical in-situ ligand exchange method of fabricating PQD@SiO_(2),the issues of chemical etching and resultant photoluminescence degradation are judiciously overcome.Employing the proposed PQD@SiO_(2),we showcase their robust usefulness in labeling chlorella,paving the way for PQD-based in-vivo photoluminescence bioimaging methodology.

关 键 词：PEROVSKITE Quantum dot PHOTOLUMINESCENCE Stability BIOIMAGING 

分 类 号：TB383[一般工业技术—材料科学与工程] O6[理学—化学]