基于“心-脾-肾”轴探讨韩祖成辨治老年痴呆用药思路  

Medications in the treatment of Alzheimer's disease based on the theory of the"heart-spleen-kidney"axis

作　　者：刘畅[1] 张晓乐 韩祖成 LIU Chang;ZHANG Xiaole;HAN Zucheng(Graduate School of Shaanxi University of Chinese Medicine,Xianyang 710042,China;Second Department of Encephalopathy,Shaanxi Provincial Hospital of Chinese medicine,Xi'an 710003,China)

机构地区：[1]陕西中医药大学研究生院,陕西咸阳710042 [2]陕西省中医医院脑病二科,西安710003

出　　处：《吉林中医药》2024年第10期1146-1150,共5页Jilin Journal of Chinese Medicine

基　　金：国家中医药管理局韩祖成全国名老中医药专家传承工作室项目(国中医药人教函[2022]75号);陕西省中医医院院级课题-苗圃计划项目(2021-25)。

摘　　要：老年痴呆病位在脑,为本虚标实之证,以心、脾、肾三脏虚损为主要病机,故基于“心-脾-肾”轴理论,针对不同证候表现,在辨证治疗的基础上,给予角药配伍组合治疗,分别以“当归-炒白术-益智仁”补虚生髓、“郁金-沉香-川牛膝”养血祛瘀、“石菖蒲-半夏-黄柏”祛痰化浊、“莲子心-茯苓-远志”交通心肾为主要代表,综合遣方用药以复脑神清明。Alzheimer's disease is located in the brain and is a syndrome of deficiency in root and excess in manifestations,with the deficiency in the heart,spleen,and kidney as its main pathogenesis.Therefore,based on the theory of the"heart-spleen-kidney"axis,according to its different symptoms,a combination therapy of triplet medicines can be given in its treatment on the basis of syndrome differentiation.The main representative formula include triplet medicines of"Chinese angelic,fried largehead atractylodes rhizome,seeds of sharp-leaf glangal fruit"for tonifying deficiency and nourishing brain marrow,"turmeric root tuber,Chinese eaglewood,medicinal cyathula root"for nourishing blood and removing blood stasis,"grassleaf sweetflag rhizomule,pinellia tuber,amur cork tree"for expelling phlegm and resolving turbidity,and"lotus plume,Indian bread,milkwort root"for restoring the normal coordination between the heart and kidney.These formula and medications are flexibly selected to restore the tranquility in the mind,and spirit.

关 键 词：心-脾-肾轴 老年痴呆 角药 名医经验 

分 类 号：R256.2[医药卫生—中医内科学]