机构地区:[1]Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX,USA [2]Hepatobiliary and General Surgery Unit,Regional Hospital Treviso,DISCOG,University of Padua,Padua,Italy [3]Division of Transplantation,Department of Surgery,University of Wisconsin School of Medicine and Public Health,Madison,WI,USA [4]Department of Thoracic Surgery and Lung Transplantation,Baylor University Medical Center,Center for Advanced Heart and Lung Disease,Dallas,TX,USA [5]Department of Surgery,University of Michigan,Ann Arbor,MI,USA [6]Division of Digestive Health and Liver Diseases,Department of Medicine,University of Miami Miller School of Medicine,Miami,FL,USA [7]Department of Cardio-Thoracic Surgery,Vanderbilt University Medical Center,Nashville,TN,USA [8]Nuffield Department of Surgical Sciences,University of Oxford,Oxford,UK [9]LifeShare Transplant Donor Services of Oklahoma,Oklahoma City,OK,USA [10]Administration,Baylor University Medical Center,Dallas,TX,USA [11]Southwest Transplant Alliance,Dallas,TX,USA [12]Department of Surgery/Transplantation,Washington University,St.Louis,MO,USA [13]Division of Transplant Surgery,Department of Surgery,Mayo Clinic Arizona,Alix School of Medicine,Phoenix,AZ,USA [14]Divisions of Transplant and Hepatobiliary Surgery,Henry Ford Hospital,Detroit,MI,USA [15]Department of Surgery,University of Minnesota,Minneapolis,MN,USA [16]General and Digestive Surgery,Hospital Universitario La Paz,IdiPAZ,Madrid,Spain
出 处:《Hepatobiliary Surgery and Nutrition》2024年第5期824-836,I0009,共14页肝胆外科与营养(英文)
摘 要:Despite a significant increase in utilization over the past decade,the number of donation after circulatory death(DCD)organs that are procured and transplanted in the United States(US)remains well below its potential.There is still room for expansion,as utilizing DCD organs to the fullest extent is currently the most viable solution to the persistent mismatch between supply and demand in transplantation.We convened a multidisciplinary transplantation summit to examine various aspects of DCD,with faculty members from around the world with clinical and academic interest in DCD donation and transplantation,including abdominal and cardiothoracic surgeons,organ procurement organization directors,hepatologists,and gastroenterologists.The conference focused on identifying barriers to DCD organ utilization and strategies to overcome these barriers.We divide the barriers to DCD utilization into three mains categories:(Ⅰ)policy and process variation;(II)logistical and transportation challenges;and(Ⅲ)higher risk perceptions related to DCD outcomes.For each barrier,we proposed a variety of solutions,providing an overview of the status of DCD donation in the US and suggestions on how to increase the use of DCD.There is a specific focus on ex situ machine perfusion,normothermic regional perfusion,and other opportunities to expand DCD utilization without negatively impacting recipient outcomes.
关 键 词:Donation after circulatory death donation(DCD donation) marginal graft donor pool machine perfusion(MP)
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