^(18)F-FDG PET-CT与增强CT、MRI鉴别诊断胰腺囊性良恶性病变的临床价值比较  

Comparison on the Clinical Value of ^(18)F-FDG PET-CT,Enhanced CT and MRI in Differential Diagnosis of Benign and Malignant Pancreatic Cystic Lesions

作　　者：李建平 陈兴龙 龚玲燕 邓侃 LI Jian-ping;CHEN Xing-long;GONG Ling-yan;DENG Kan(Department of Nuclear Medicine,Shanghai Yongci Rehabilitation Hospital,Shanghai 201107,China)

机构地区：[1]上海永慈康复医院核医学科,上海201107

出　　处：《中国CT和MRI杂志》2024年第10期103-105,共3页Chinese Journal of CT and MRI

摘　　要：目的 探讨18氟-脱氧葡糖糖正电子发射型计算机断层扫描(^(18)F-FDG PET-CT)增强CT、磁共振成像(MRI)在鉴别诊断胰腺囊性良恶性病变的临床价值。方法回顾性分析2021年2月-2023年1月医院收治的80例胰腺囊性病变患者的影像学资料,分析^(18)F-FDG PET-CT、增强CT、MRI对胰腺囊性良恶性病变评估价值。结果本研究中恶性病变35例、良性45例,增强CT检查中,6例黏液性囊性瘤、2例导管内乳头状黏液性肿瘤因形态规则、边界清晰误诊为良性病灶;5例假性囊肿、1例真性囊肿因边界不清晰、边缘强化被误诊为恶性病灶。MRI检查中,5例黏液性囊性瘤在常规平扫时显示不明显、呈不规则状分布,被误诊为良性病灶;4例假性囊肿、1例真性囊肿因边界不清晰或强化不均匀被误诊为恶性病灶。^(18)F-FDG PET-CT检查中2例导管内乳头状粘液瘤因病灶最大标准化摄取值(SUVmax)≤2.5被误诊为良性病灶;1例浆液性囊性瘤因SUVmax>2.5被误诊为恶性病灶。^(18)F-FDG PET-CT检测的准确率、特异性分别为9 6.25%、97.14%,明显高于增强CT、MRI检测,^(18)F-FDG PET-CT检测的敏感性为95.56%显著高于增强CT(P<0.05)。结论与CT和MRI检查相比,^(18)F-FDG PET-CT可以为胰腺囊性良恶性病变提供更为准确的评估,对患者治疗方案的选择预后预测提供数据支持。Objective To explo re the clinical value of ^(18)F-fluorodeoxygiucose positro n-emission tomography/computed tomography(^(18)F-FDG PET-CT),enhanced CT and magnetic resonance imaging(MRI) in the differential diagnosis of benign and malignant pancreatic cystic lesions.Methods The imaging data of 80 patients with pancreatic cystic lesions who were admitted to the hospital were retrospectively analyzed between February 2021 and January 2023.The evaluation value of ^(18)F-FDG PET-CT,enhanced CT and MRI for benign and malignant pancreatic cystic lesions was analyzed.Results In the80 patients,there were 35 cases with malignant lesions and 45 cases with benign lesions.In enhanced CT examination,there were 6 cases with mucinous cystic tumors,2 cases with intraductal papillary mucinous tumors(misdiagnosed as benign lesions due to regular morphology and clear borders),5cases with pseudocysts and 1 case with true cysts(misdiagnosed as malignant lesions due to unclear borders and enhanced edges).In MRI examination,there were 5 cases with mucinous cystic tumors(misdiagnosed as benign lesions),showing inconspicuous display,flaky or irregular distribution in routine plain sca n,4 cases with pseudocysts and and 1 case with true cysts(misdiagnosed as malignant lesions due to unclear borders or uneven enhancement).In ^(18)F-FDG PET-CT exa mination,there were 2cases with int raductal papillary mucinous tumors [misdiagnosed as benign lesions due to standa rdized uptake value(SUVmax) not greater than 2.5) and 1 case with serous cystic tumor(misdiagnosed as malignant lesions due to SUVmax greater than 2.5).The accu racy and specificity rates of ^(18)F-FDG PETCT detection were 96.25% and 97.14%,which were significantly higher than those of enhanced CT and MRI.The sensitivity rate of ^(18)F-FDG PET-CT detection was 95.56%,significantly higher than that of enhanced CT(P<0.05).Conclusion Compared with CT and MRI,18F-FDG PET-CT can provide more accurate assessment for benign and malignant pancreatic cystic lesions,which provides data suppor

关 键 词：胰腺囊性病变 正电子发射型计算机断层扫描 CT 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]