Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID  

作　　者：Ming Guo Shunlai Shang Mengfei Li Guangyan Cai Ping Li Xiangmei Chen Qinggang Li 

机构地区：[1]Department of Nephrology,First Medical Center of Chinese PLA General Hospital,State Key Laboratory of Kidney Diseases,National Clinical Research Center for Kidney Diseases,Beijing Key Laboratory of Kidney Diseases Research,Beijing 100853,China [2]Department of Nephrology,China-Japan Friendship Hospital,Beijing,China [3]Haihe Laboratory of Cell Ecosystem,China

出　　处：《Medical Review》2024年第5期367-383,共17页医学评论（英文）

基　　金：supported by the National Natural Science Foundation of China (81830019);Beijing Natural Science Foundation (7202188);Haihe Laboratory of Cell Ecosystem Innovation Fund (22HHXBSS00002);National Key R&D Program of China (2022YFC3602005);Cross-sectional project of China-Japan Friendship Hospital (Certificate Number:2023-HX-JC-10 and 2023-HX-103);International Association of Chinese Nephrologists Research Grant (No.IACNRG-01);the Open Grant from the Pingyuan Laboratory (2023PY-0P-0203);Young Elite Scientists Spon-sorship Program by CAST (2023QNRC001);Beijing Natural Science Foundation (7244407);Supported by the China Postdoctoral Science Foundation under Grant Number 2023M733986 and 2023T160741.

摘　　要：COVID-19 posed a major challenge to the healthcare systemandresourcesworldwide.Thepopularizationofvaccines and the adoption of numerous prevention and control measures enabled the gradual end of the COVID-19 pandemic.However,successive occurrence of autoimmune diseases in patients with COVID-19cannot beoverlooked.Long COVID has been themajor focus of research due to the long duration of different symptoms and the variety of systems involved.Autoimmunity may play a crucial role in the pathogenesis of long COVID.Here,we reviewed several autoimmune disorders occurring after COVID-19 infection and the pathogenesis of long COVID.

关 键 词：COVID-19 SARS-CoV-2 long COVID AUTOIMMUNITY 

分 类 号：R563.1[医药卫生—呼吸系统]