Regenerative rehabilitation:a novel multidisciplinary field to maximize patient outcomes  

作　　者：Chunchu Deng Fatima Aldali Hongmei Luo Hong Chen 

机构地区：[1]Department of Rehabilitation Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China

出　　处：《Medical Review》2024年第5期413-434,共22页医学评论（英文）

基　　金：funded by grants from the National Natural Science Foundation of China (82171422);Key Research and Development Project of Hubei Province of China (2022BCA028).

摘　　要：Regenerative rehabilitation is a novel and rapidly developing multidisciplinaryfield that converges regenerative medicine and rehabilitation science,aiming to maximize the functions of disabled patients and their independence.While regenerative medicine provides state-of-the-art technologies that shed light on difficult-to-treated diseases,regenerative rehabilitation offers rehabilitation interventions to improve the positive effects of regenerative medicine.However,regenerative scientists and rehabilitation professionals focus on their aspects without enough exposure to advances in each other’sfield.This disconnect has impeded the development of thisfield.Therefore,this reviewfirst introduces cutting-edge tech-nologies such as stem cell technology,tissue engineering,biomaterial science,gene editing,and computer sciences that promote the progress pace of regenerative medicine,followed by a summary of preclinical studies and examples of clinical investigations that integrate rehabilitative methodologies into regenerative medicine.Then,challenges in thisfield are discussed,and possible solutions are provided for future directions.We aim to provide a platform for regenerative and rehabilitative professionals and clinicians in other areas to better understand the progress of regenerative rehabilitation,thus contributing to the clinical translation and management of innovative and reliable therapies.

关 键 词：regenerative rehabilitation stem cell therapy rehabilitation strategies enhanced motor functions 

分 类 号：R49[医药卫生—康复医学]